| Long name: |
Polyclonal Antibody to CASP2 And RIPK1 Domain Containing Adaptor With Death Domain Protein (CRADD) |
| Antigen: |
CASP2 And RIPK1 Domain Containing Adaptor With Death Domain Protein (CRADD) |
| Other names: |
CASP2 and RIPK1 domain containing adaptor with death domain, Caspase and RIP adapter with death domain, Death domain-containing protein CRADD, RIP-associated ICH1/CED3-homologous protein with death domain, RIP-associated protein with a death domain, RIP-associated protein with a death domain, caspase and RIP adaptor with death domain, death adaptor molecule RAIDD, death domain-containing protein CRADD, CASP2 and RIPK1 domain containing adaptor with death domain |
| Gene name: |
CRADD, CASP2 And RIPK1 Domain Containing Adaptor With Death Domain Protein (CRADD) |
| Gene synonims: |
CRADD, MRT34, RAIDD, RAIDD, CRADD |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
, CRADD, It has been selected for its ability to recognize CRADD in immunohistochemical staining andwestern blotting, The antibody is a rabbit polyclonal antibody raised against CRADD, This is an antibody designed to detect CASP2 And RIPK1 Domain Containing Adaptor With Death Domain Protein (CRADD) |
| Purification method: |
This antibody was purified via Affinity Chromatography |
| Form/Appearance: |
containing 0, pH7, 02% NaN3, 4, 50% glycerol, Supplied as solution form in PBS |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Immunohistochemistry (IHC) - Formalin/Paraffin, Western Blot (WB), Immunocytochemistry (ICC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Gene target: |
CASP2 RIPK1 Domain Adaptor With Death Domain Protein (CRADD) |
| Short name: |
Anti- CASP2 And RIPK1 Domain Adaptor With Death Domain Protein (CRADD) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
apoptosis-related cysteine peptidase And receptor (TNFRSF)-interacting serine-threonine kinase 1 Domain Containing Adaptor including Death Domain Protein (CASP2 and RIPK1 domain containing adaptor including death domain) (Antibody to), Antibody to caspase 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CASP-2 and ICH1 and NEDD-2 and NEDD2 and PPP1R57, CASP2 and IDBG-45836 and ENSG00000106144 and 835, CASP2 and RIPK1 domain containing adaptor with death domain, CRADD and IDBG-51368 and ENSG00000169372 and 8738, CRADD and IDBG-630849 and ENSBTAG00000005107 and 615788, Casp2 and IDBG-141522 and ENSMUSG00000029863 and 12366, Cradd and IDBG-187068 and ENSMUSG00000045867 and 12905, MRT34 and RAIDD, Plasma membranes, RIP and RIP1, RIPK1 and IDBG-57326 and ENSG00000137275 and 8737, RIPK1 and IDBG-636679 and ENSBTAG00000006378 and 504727, Ripk1 and IDBG-143710 and ENSMUSG00000021408 and 19766, apoptosis-related cysteine peptidase, bridging, bridging and also this GO :0070513 : death domain binding, bridging and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0070513 and death domain binding and molecular function this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, cysteine-type endopeptidase activity involved in apoptotic process, nuclei, nuclei, protein binding, receptor (TNFRSF)-interacting serine-threonine kinase 1, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007165 and signal transduction and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0030674 and protein binding, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007420 and brain development and biological process this GO :0007568 and aging and biological process this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0016020 and membrane and cellular component this GO :0016485 and protein processing and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0035234 and ectopic germ cell programmed cell death and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0097153 and cysteine-type endopeptidase activity involved in apoptotic process and molecular function this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097194 and execution phase of apoptosis and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, this GO :0001554 and luteolysis and biological process this GO :0003407 and neural retina development and biological process this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005123 and death receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0016772 and transferase activity, this GO :0002020 and protease binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006977 and DNA damage response, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005515 : protein binding and also this GO :0030674 : protein binding, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0019899 : enzyme binding and also this GO :0019904 : protein domain specific binding and also this GO :0097153 : cysteine-type endopeptidase activity involved in apoptotic process, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005123 : death receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005123 : death receptor binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008234 : cysteine-type peptidase activity, this GO :0016772 : transferase activity, this GO :0019899 : enzyme binding, this GO :0019904 : protein domain specific binding, this GO :0030674 : protein binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0032403 : protein complex binding, this GO :0042802 : identical protein binding, this GO :0070513 : death domain binding, this GO :0070513 : death domain binding, this GO :0097153 : cysteine-type endopeptidase activity involved in apoptotic process, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0032403 : protein complex binding and also this GO :0042802 : identical protein binding and also this GO :0070513 : death domain binding, transferring phosphorus-containing groups and molecular function this GO :0031264 and death-inducing signaling complex and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0036289 and peptidyl-serine autophosphorylation and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043068 and positive regulation of programmed cell death and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0044257 and cellular protein catabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051347 and positive regulation of transferase activity and biological process this GO :0060545 and positive regulation of necroptotic process and biological process this GO :0070231 and T cell apoptotic process and biological process this GO :0070266 and necroptotic process and biological process this GO :0070513 and death domain binding and molecular function this GO :0070926 and regulation of ATP:ADP antiporter activity and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097342 and ripoptosome and cellular component this GO :0097343 and ripoptosome assembly and biological process this GO :0097527 and necroptotic signaling pathway and biological process this GO :1901026 and ripoptosome assembly involved in necroptotic process and biological process this GO :1990000 and amyloid fibril formation and biological process this GO :2000377 and regulation of reactive oxygen species metabolic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, 103474 and IDBG-636898 and ENSBTAG00000018159 and 531419, caspase 2 |
| Identity: |
2340 |
| Gene: |
CRADD |
More about : CRADD |
| Long gene name: |
CASP2 and RIPK1 domain containing adaptor with death domain |
| Synonyms: |
RAIDD |
| Synonyms name: |
RIP-associated ICH1/CED3-homologous protein with death domain |
| Locus: |
12q22 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
U84388 |
| Entrez gene record: |
8738 |
| Pubmed identfication: |
8985253 9044836 |
| RefSeq identity: |
NM_003805 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000170322 |