| Long name: |
ALEXA FLUOR 488 Conjugated, EML4 Polyclonal Antibody |
| Also known as: |
Anti-EML4 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EML4 |
| Specificity: |
This is a highly specific antibody against EML4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EML4/C2orf180 |
| Gene ID Number: |
27436 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
C2orf2 or ROPP120, Due to a chromosomal inversion with chromosome 2p, ELP120, EML4 (Echinoderm microtubule-associated protein-like 4), EML4 is thought to modify the assembly dynamics of microtubules, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules, Expressed at high levels during mitosis, also known as EMAPL4, cell motility, is a 981 amino acid cytoplasmic protein that contains nine WD repeats, producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer, specifically altering microtubules to become longer and more flexible, spindle formation and chromosome movements, Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
ROPP120 ELP120 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the EML4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
EML4 |
| Short name: |
EML4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, EML4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1316 |
| Gene: |
EML4 |
More about : EML4 |
| Long gene name: |
echinoderm microtubule associated protein like 4 |
| Synonyms gene: |
C2orf2 |
| Locus: |
2p21 |
| Discovery year: |
2000-01-31 |
| GenBank acession: |
AF177377 |
| Entrez gene record: |
27436 |
| RefSeq identity: |
NM_019063 |
| Classification: |
WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000128603 |