| Long name: |
D53 Primary Polyclonal Antibody |
| Also known as: |
D53 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
D53 |
| Specificity: |
This is a highly specific antibody against D53 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TPD52L1/D53 |
| Gene ID number: |
7164 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
D53, D53 intereacts with 14-3-3, D53 may function as a signaling intermediate and/or regulator of vesicle trafficking and cell proliferation, Expression of D53 is highly upregulated at the G2/M phase transition in breast cancer cell lines, a negative regulator of the G2/M transition, also referred to as tumor protein D52-like 1 (TPD52L1), and deregulated expression of this protein can adversely affect the completion of mitosis, and the timing of mitotic entry is tightly regulated to guarantee correct chromosome segregation, in breast cancer cells, is a coiled-coil motif-bearing member of the D52 tumor protein family, The cell commits to dividing during the G2/M phase transition |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
D54, TPD52L2 TPD53_HUMAN, Tpd52l1, Tumor protein D52 like 1, Tumor protein D52 like 2, Tumor protein D52-like 1, Tumor protein D53, Tumor protein D54, hD53, hD54, D53 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
D53 |
| Short name: |
D53 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
D53 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12006 |
| Gene: |
TPD52L1 |
More about : TPD52L1 |
| Long gene name: |
tumor protein D52-like 1 |
| Synonyms: |
D53 hD53 |
| Locus: |
6q22-q23 |
| Discovery year: |
1996-04-30 |
| GenBank acession: |
U44427 |
| Pubmed identfication: |
8812487 16112108 |
| Havana BLAST/BLAT: |
OTTHUMG00000015505 |