| Long name: |
Biotin Conjugated, BIN2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BIN2 |
| Specificity: |
This is a highly specific antibody against BIN2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human BIN2/BRAP1 |
| Gene ID number: |
51411 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis, BIN1 also interacts with the transcription factors c-Myc and MyoD, BIN1 and BIN2 are BAR proteins that share 61% sequence similarity, BIN2, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region, BIN2 shows preferred expression in tissues of hematopoietic origin, In contrast to BIN1, There are two isoforms of BIN2 that are produced as a result of alternative splicing events, also known as Breast cancer-associated protein 1, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes, colon, is a 565 amino acid protein that interacts with BIN1, lymphoid and granulocytic cells, placenta, potentially functioning as a tumor suppressor, thymus, with high levels found in spleen, BAR proteins are characterized by a common N-terminal BAR (bin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
BRAP-1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
BIN2 Conjugated |
| Short name: |
Conjugated, BIN2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, BIN2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1053 |
| Gene: |
BIN2 |
More about : BIN2 |
| Long gene name: |
bridging integrator 2 |
| Locus: |
12q13, 13 |
| Discovery year: |
2000-05-25 |
| GenBank acession: |
AF146531 |
| Entrez gene record: |
51411 |
| Pubmed identfication: |
10903846 |
| Classification: |
N-BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000185197 |