| Long name: |
Catalytic (GCLC), Polyclonal Antibody to Glutamate Cysteine Ligase |
| Antigen: |
Catalytic (GCLC), Glutamate Cysteine Ligase |
| Other names: |
CG2259 gene product from transcript CG2259-RA, CG2259-PA, CG2259-PB, GCS, Gamma-ECS, Gamma-glutamylcysteine synthetase, Gclc-PA, Gclc-PB, Glutamate--cysteine ligase, Glutamate-cysteine ligase catalytic subunit, Glutamate-cysteine ligase catalytic subunit, gamma-Glutamylcysteine synthetase, gamma-Glutamylcysteine synthetase catalytic subunit, gamma-glutamylcysteine ligase, glutamate cysteine ligase, glutamate-cysteine ligase, isoform B, Glutamate-cysteine ligase catalytic subunit |
| Gene name: |
Catalytic (GCLC) , GCLC, Glutamate Cysteine Ligase |
| Gene synonims: |
2259, CG2259, DmGCLC, DmGCS, DmGCSh, DmelCG2259, GCL, GCLc, GCS, GCSh, GCSh, Gclc, Gcs, Gcsh, Gclc |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
, Catalytic (GCLC) , GCLC, It has been selected for its ability to recognize GCLC in immunohistochemical staining andwestern blotting, The antibody is a rabbit polyclonal antibody raised against GCLC, This is an antibody designed to detect Glutamate Cysteine Ligase |
| Purification method: |
This antibody was purified via Affinity Chromatography |
| Form/Appearance: |
containing 0, pH7, 02% NaN3, 4, 50% glycerol, Supplied as solution form in PBS |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Immunohistochemistry (IHC) - Formalin/Paraffin, Western Blot (WB), Immunocytochemistry (ICC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Gene target: |
Catalytic (GCLC), Glutamate Cysteine Ligase |
| Short name: |
Catalytic (GCLC) Antibody, Anti- Glutamate Cysteine Ligase |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Catalytic (glutamate-cysteine ligase, catalytic subunit) (Antibody to), Antibody to Glutamate Cysteine Ligase |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, DNA-templated and biological process this GO :0046685 and response to arsenic-containing substance and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050662 and coenzyme binding and molecular function this GO :0050880 and regulation of blood vessel size and biological process this GO :0051409 and response to nitrosative stress and biological process this GO :0051900 and regulation of mitochondrial depolarization and biological process this GO :1901687 and glutathione derivative biosynthetic process and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, GCL and GCS and GLCL and GLCLC, GCLC and IDBG-628748 and ENSBTAG00000015571 and 512468, GCLC and IDBG-91041 and ENSG00000001084 and 102724876, Gclc and IDBG-186028 and ENSMUSG00000032350 and 14629, catalytic subunit, coenzyme binding, this GO :0000096 and sulfur amino acid metabolic process and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0004357 and glutamate-cysteine ligase activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006534 and cysteine metabolic process and biological process this GO :0006536 and glutamate metabolic process and biological process this GO :0006749 and glutathione metabolic process and biological process this GO :0006750 and glutathione biosynthetic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0009408 and response to heat and biological process this GO :0009410 and response to xenobiotic stimulus and biological process this GO :0009725 and response to hormone and biological process this GO :0016595 and glutamate binding and molecular function this GO :0017109 and glutamate-cysteine ligase complex and cellular component this GO :0019852 and L-ascorbic acid metabolic process and biological process this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043531 and ADP binding and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045454 and cell redox homeostasis and biological process this GO :0045892 and negative regulation of transcription, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004357 : glutamate-cysteine ligase activity and also this GO :0005524 : ATP binding and also this GO :0016595 : glutamate binding and also this GO :0043531 : ADP binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0050662 : coenzyme binding, this GO :0004357 : glutamate-cysteine ligase activity, this GO :0005524 : ATP binding, this GO :0016595 : glutamate binding, this GO :0043531 : ADP binding, this GO :0046982 : protein heterodimerization activity, this GO :0050662 : coenzyme binding, 2729, glutamate-cysteine ligase |
| Identity: |
4311 |
| Gene: |
GCLC |
More about : GCLC |
| Long gene name: |
glutamate-cysteine ligase catalytic subunit |
| Synonyms gene: |
GLCLC GLCL |
| Synonyms gene name: |
catalytic subunit , glutamate-cysteine ligase |
| Synonyms: |
GCS |
| Locus: |
6p12, 1 |
| Discovery year: |
1993-11-24 |
| GenBank acession: |
M90656 |
| Entrez gene record: |
2729 |
| Pubmed identfication: |
1350904 |
| Havana BLAST/BLAT: |
OTTHUMG00000160220 |