| Long name: |
Polyclonal Antibody to Suppressors Of Cytokine Signaling 3 (SOCS3) |
| Antigen: |
Suppressors Of Cytokine Signaling 3 (SOCS3) |
| Other names: |
CIS-3, Cytokine-inducible SH2 protein 3, STAT-induced STAT inhibitor 3, STAT-induced STAT inhibitor 3, Suppressor of cytokine signaling 3, cytokine-inducible SH2 protein 3, suppressor of cytokine signaling 3, suppressor of cytokine signaling 3, suppressor of cytokine signaling 3 |
| Gene name: |
SOCS3, Suppressors Of Cytokine Signaling 3 (SOCS3) |
| Gene synonims: |
ATOD4, CIS-3, CIS3, CIS3, Cish3, SOCS-3, SOCS-3, SOCS3, SSI-3, SSI-3, SSI3, SSI3, SOCS3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
, It has been selected for its ability to recognize SOCS3 in immunohistochemical staining andwestern blotting, SOCS3, The antibody is a rabbit polyclonal antibody raised against SOCS3, This is an antibody designed to detect Suppressors Of Cytokine Signaling 3 (SOCS3) |
| Purification method: |
This antibody was purified via Affinity Chromatography |
| Form/Appearance: |
containing 0, pH7, 02% NaN3, 4, 50% glycerol, Supplied as solution form in PBS |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Immunohistochemistry (IHC) - Formalin/Paraffin, Western Blot (WB), Immunocytochemistry (ICC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Description: |
By understanding cell signaling, Errors in cellular information processing are responsible for diseases such as cancer, The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, and diabetes, and immunity as well as normal tissue homeostasis, artificial tissues may be created, autoimmunity, diseases may be treated effectively and, theoretically, tissue repair, Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions |
| Gene target: |
Suppressors Of Cytokine Signaling 3 (SOCS3) |
| Short name: |
Anti- Suppressors Of Cytokine Signaling 3 (SOCS3) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Antibody to Suppressors on Cytokine Signaling 3 (suppressor on cytokine signaling 3) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATOD4 and CIS3 and Cish3 and SOCS-3 and SSI-3 and SSI3, Cytoplasm, SOCS3 and IDBG-647946 and ENSBTAG00000008441 and 282081, SOCS3 and IDBG-70676 and ENSG00000184557 and 9021, Socs3 and IDBG-214604 and ENSMUSG00000053113 and 12702, protein binding, this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0040008 and regulation of growth and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0060670 and branching involved in labyrinthine layer morphogenesis and biological process this GO :0060674 and placenta blood vessel development and biological process this GO :0060707 and trophoblast giant cell differentiation and biological process this GO :0060708 and spongiotrophoblast differentiation and biological process, this GO :0004860 : protein kinase inhibitor activity, this GO :0004860 : protein kinase inhibitor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, suppressor of cytokine signaling 3 |
| Identity: |
19391 |
| Gene: |
SOCS3 |
More about : SOCS3 |
| Long gene name: |
suppressor of cytokine signaling 3 |
| Synonyms: |
SSI-3 CIS3 SOCS-3 Cish3 |
| Locus: |
17q25, 3 |
| Discovery year: |
2002-11-13 |
| GenBank acession: |
AB004904 |
| Entrez gene record: |
9021 |
| Pubmed identfication: |
9266833 9344848 |
| Classification: |
Suppressors of cytokine signaling SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000177513 |
| Locus Specific Databases: |
LRG_619 |