| DNA lentivector for transduction information: |
GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions, Vectors with selection markers like kanamycin, our 3rd Generation Packaging mixture, pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C, puromycin or cumate are available, Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
PSEN2 Lentiviral Vector (CMV) (pLenti-GIII-CMV) |
| Short name: |
PSEN2 Lentiviral Vector ( ) (CMV) (pLenti-GIII-CMV) |
| Technique: |
Vectors |
| Species: |
Humans, Human |
| Alternative name: |
sapiens) (cytomegalovirus) (pLenti-GIII-cytomegalovirus), presenilin 2 (Alzheimer disease 4) Lentiviral integrating Desoxyribonucleic acid sequence (H |
| Alternative to gene target: |
AD3L and AD4 and CMD1V and PS2 and STM2, PSEN2 and IDBG-107053 and ENSG00000143801 and 5664, PSEN2 and IDBG-631143 and ENSBTAG00000013197 and 282010, Psen2 and IDBG-207109 and ENSMUSG00000010609 and 19165, nuclei, protein binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000776 and kinetochore and cellular component this GO :0001666 and response to hypoxia and biological process this GO :0001708 and cell fate specification and biological process this GO :0001756 and somitogenesis and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001942 and hair follicle development and biological process this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0002286 and T cell activation involved in immune response and biological process this GO :0002573 and myeloid leukocyte differentiation and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004190 and aspartic-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005637 and nuclear inner membrane and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006508 and proteolysis and biological process this GO :0006509 and membrane protein ectodomain proteolysis and biological process this GO :0006816 and calcium ion transport and biological process this GO :0007176 and regulation of epidermal growth factor-activated receptor activity and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007220 and Notch receptor processing and biological process this GO :0007611 and learning or memory and biological process this GO :0007613 and memory and biological process this GO :0009986 and cell surface and cellular component this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016485 and protein processing and biological process this GO :0021904 and dorsal/ventral neural tube patterning and biological process this GO :0030018 and Z disc and cellular component this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030424 and axon and cellular component this GO :0030426 and growth cone and cellular component this GO :0030900 and forebrain development and biological process this GO :0031293 and membrane protein intracellular domain proteolysis and biological process this GO :0031333 and negative regulation of protein complex assembly and biological process this GO :0031594 and neuromuscular junction and cellular component this GO :0032091 and negative regulation of protein binding and biological process this GO :0032469 and endoplasmic reticulum calcium ion homeostasis and biological process this GO :0035253 and ciliary rootlet and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0040011 and locomotion and biological process this GO :0042640 and anagen and biological process this GO :0042987 and amyloid precursor protein catabolic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043198 and dendritic shaft and cellular component this GO :0043234 and protein complex and cellular component this GO :0043393 and regulation of protein binding and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045121 and membrane raft and cellular component this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048538 and thymus development and biological process this GO :0048854 and brain morphogenesis and biological process this GO :0050435 and beta-amyloid metabolic process and biological process this GO :0050820 and positive regulation of coagulation and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051604 and protein maturation and biological process this GO :0060048 and cardiac muscle contraction and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :1902043 and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2001234 and negative regulation of apoptotic signaling pathway and biological process, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004190 : aspartic-type endopeptidase activity and also this GO :0005515 : protein binding, this GO :0004190 : aspartic-type endopeptidase activity, this GO :0005515 : protein binding, presenilin 2 (Alzheimer disease 4) |
| Identity: |
9509 |
| Gene: |
PSEN2 |
More about : PSEN2 |
| Long gene name: |
presenilin 2 |
| Synonyms gene: |
AD4 |
| Synonyms gene name: |
Alzheimer disease 4 |
| Synonyms: |
AD3L STM2 PS2 |
| Locus: |
1q42, 13 |
| Discovery year: |
1995-08-30 |
| GenBank acession: |
BC006365 |
| Entrez gene record: |
5664 |
| Pubmed identfication: |
7638621 |
| RefSeq identity: |
NM_000447 |
| Havana BLAST/BLAT: |
OTTHUMG00000037563 |
| Locus Specific Databases: |
Alzheimer Disease &, Frontotemporal Dementia Mutation Database LRG_225 |