| Long name: |
Recombinant Bubalus bubalis Interleukin-12 subunit beta (IL12B) |
| Alternative names: |
CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, Interleukin-12 subunit beta, Interleukin-12 subunit beta |
| Gene name: |
IL12B |
| Other gene names: |
CLMF p40, IL-12B, IL12B |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Interleukin-12 subunit beta (IL12B) is a recombinant protein expressed in Yeast |
| Product category: |
Recombinant Proteins |
| Expression system: |
Yeast |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Gene target: |
Bubalus bubalis Interleukin-12 subunit beta (IL12B) |
| Short name: |
Bubalus bubalis Interleukin-12 subunit beta (IL12B) |
| Alternative name: |
cytotoxic lymphocyte maturation factor 2, p40)), Bubalus bubalis Interleukin-12 functionnal sequence b (interleukin 12B (natural killer cellular stimulatory factor 2 |
| Alternative to gene target: |
CLMF and CLMF2 and IL-12B and IMD28 and IMD29 and NKSF and NKSF2, Extracellular, IL12B and IDBG-55893 and ENSG00000113302 and 3593, IL12B and IDBG-646420 and ENSBTAG00000004741 and 281857, Il12b and IDBG-164545 and ENSMUSG00000004296 and 16160, cytotoxic lymphocyte maturation factor 2, p40), protein heterodimerization activity, this GO :0001916 and positive regulation of T cell mediated cytotoxicity and biological process this GO :0002230 and positive regulation of defense response to virus by host and biological process this GO :0002323 and natural killer cell activation involved in immune response and biological process this GO :0002827 and positive regulation of T-helper 1 type immune response and biological process this GO :0002860 and positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target and biological process this GO :0002862 and negative regulation of inflammatory response to antigenic stimulus and biological process this GO :0004896 and cytokine receptor activity and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005126 and cytokine receptor binding and molecular function this GO :0005143 and interleukin-12 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007050 and cell cycle arrest and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0010224 and response to UV-B and biological process this GO :0010535 and positive regulation of activation of JAK2 kinase activity and biological process this GO :0016020 and membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019233 and sensory perception of pain and biological process this GO :0019953 and sexual reproduction and biological process this GO :0030101 and natural killer cell activation and biological process this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0032700 and negative regulation of interleukin-17 production and biological process this GO :0032725 and positive regulation of granulocyte macrophage colony-stimulating factor production and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032740 and positive regulation of interleukin-17 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032816 and positive regulation of natural killer cell activation and biological process this GO :0032819 and positive regulation of natural killer cell proliferation and biological process this GO :0032946 and positive regulation of mononuclear cell proliferation and biological process this GO :0034105 and positive regulation of tissue remodeling and biological process this GO :0034393 and positive regulation of smooth muscle cell apoptotic process and biological process this GO :0042035 and regulation of cytokine biosynthetic process and biological process this GO :0042088 and T-helper 1 type immune response and biological process this GO :0042093 and T-helper cell differentiation and biological process this GO :0042095 and interferon-gamma biosynthetic process and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042164 and interleukin-12 alpha subunit binding and molecular function this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042510 and regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0042520 and positive regulation of tyrosine phosphorylation of Stat4 protein and biological process this GO :0042523 and positive regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042832 and defense response to protozoan and biological process this GO :0043382 and positive regulation of memory T cell differentiation and biological process this GO :0043514 and interleukin-12 complex and cellular component this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045519 and interleukin-23 receptor binding and molecular function this GO :0045672 and positive regulation of osteoclast differentiation and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0050671 and positive regulation of lymphocyte proliferation and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0051135 and positive regulation of NK T cell activation and biological process this GO :0051142 and positive regulation of NK T cell proliferation and biological process this GO :0051607 and defense response to virus and biological process this GO :0070743 and interleukin-23 complex and cellular component this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :2000318 and positive regulation of T-helper 17 type immune response and biological process this GO :2000330 and positive regulation of T-helper 17 cell lineage commitment and biological process, this GO :0004896 : cytokine receptor activity, this GO :0004896 : cytokine receptor activity and also this GO :0005125 : cytokine activity and also this GO :0005126 : cytokine receptor binding and also this GO :0005143 : interleukin-12 receptor binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0042164 : interleukin-12 alpha subunit binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0045519 : interleukin-23 receptor binding and also this GO :0046982 : protein heterodimerization activity, this GO :0005125 : cytokine activity, this GO :0005126 : cytokine receptor binding, this GO :0005143 : interleukin-12 receptor binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0042164 : interleukin-12 alpha subunit binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0045519 : interleukin-23 receptor binding, this GO :0046982 : protein heterodimerization activity, interleukin 12B (natural killer cell stimulatory factor 2 |
| Identity: |
5970 |
| Gene: |
IL12B |
More about : IL12B |
| Long gene name: |
interleukin 12B |
| Synonyms gene: |
NKSF2 |
| Synonyms gene name: |
cytotoxic lymphocyte maturation factor 2, interleukin 12B (natural killer cell stimulatory factor 2, p40) |
| Synonyms: |
CLMF IL-12B NKSF CLMF2 |
| Synonyms name: |
40 kD subunit interleukin-12 beta chain IL12, natural killer cell stimulatory factor-2 cytotoxic lymphocyte maturation factor 2, p40 interleukin 12, p40 natural killer cell stimulatory factor, subunit p40 |
| Locus: |
5q33, 3 |
| Discovery year: |
1991-08-08 |
| GenBank acession: |
M65290 |
| Entrez gene record: |
3593 |
| Pubmed identfication: |
1673147 |
| RefSeq identity: |
NM_002187 |
| Classification: |
Interleukins Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130307 |
| Locus Specific Databases: |
IL12Bbase: Mutation registry for Interleukin-12 (IL-12) p40 deficiency LRG_71 |