| Long name: |
EPCR Primary Polyclonal Antibody |
| Also known as: |
EPCR PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
EPCR |
| Specificity: |
This is a highly specific antibody against EPCR |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EPCR/CD201 |
| Gene ID number: |
10544 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is an N glycosylated type I membrane protein that enhances the activation of protein C, It is expressed strongly in the endothelial cells of arteries and veins in heart and lung, It is overexpressed in several human non-Pgp multidrug resistant (MDR) tumor cell lines, Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug resistance is unclear, a serine protease activated by and involved in the blood coagulation pathway, as well as with late fetal loss during pregnancy, EPCR is a receptor for activated protein C |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APC receptor, APCR, CCCA, CCD41, CD201, CD201 antigen, EPCR_HUMAN, Endothelial cell protein C receptor, MGC23024, PROCR, centrocyclin, Activated protein C receptor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
EPCR |
| Short name: |
EPCR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
EPCR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9452 |
| Gene: |
PROCR |
More about : PROCR |
| Long gene name: |
protein C receptor |
| Synonyms gene name: |
endothelial , protein C receptor |
| Synonyms: |
EPCR CCD41 CD201 |
| Locus: |
20q11, 22 |
| Discovery year: |
2000-06-26 |
| GenBank acession: |
L35545 |
| Entrez gene record: |
10544 |
| Pubmed identfication: |
7929370 10518938 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000032323 |
| Locus Specific Databases: |
LRG_638 |