| Long name: |
TNNI3K Primary Polyclonal Antibody |
| Also known as: |
TNNI3K PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TNNI3K |
| Specificity: |
This is a highly specific antibody against TNNI3K |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TNNI3K |
| Gene ID number: |
51086 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Administration of TNNI3K to mice with myocardial infarction improves cardiac performance and attentuates ventricular remodeling, Overexpression of TNNI3K leads to improved cardiac function by enhancing beating frequency and increasing contractile force and epinephrine response, TNNI3K suppresses phosphorylation of cardiac troponin I and p38/JNK-mediated apoptosis, There are four isoforms of TNNI3K that are produced as a result of alternative splicing events, also known as CARK, is a 936 amino acid serine/threonine-protein kinase that is highly expressed in heart, suggesting that TNNI3K could be a promising target in the treatment of cardiac diseases, therefore protecting the myocardium from ischemic injury, TNNI3K |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CARK, MGC142099, MGC33828, Serine/threonine protein kinase TNN13K, Serine/threonine-protein kinase TNNI3K, TNI3K_HUMAN, TNNI3 interacting kinase, TNNI3-interacting kinase, Tnni3k, Cardiac ankyrin repeat kinase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TNNI3K |
| Short name: |
TNNI3K Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TNNI3K (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19661 |
| Gene: |
TNNI3K |
More about : TNNI3K |
| Long gene name: |
TNNI3 interacting kinase |
| Synonyms: |
CARK |
| Locus: |
1p31, 1 |
| Discovery year: |
2004-01-19 |
| GenBank acession: |
AF116826 |
| Entrez gene record: |
51086 |
| Pubmed identfication: |
12721663 |
| RefSeq identity: |
NM_015978 |
| Havana BLAST/BLAT: |
OTTHUMG00000171318 |
| Locus Specific Databases: |
LRG_678 |