| Long name: |
Cy5, 5 Conjugated, AMPK gamma 1/2/3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AMPK gamma 1/2/3 |
| Specificity: |
This is a highly specific antibody against AMPK gamma 1/2/3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
280-330/569 |
| Subcellular location: |
Cytoplasm, Nucleus, Extracellular |
| Source: |
³, 2, KLH conjugated synthetic peptide derived from human PRKAG2/AMPKÎ |
| Gene ID number: |
5571, 51422, 53632 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein, Human AMPKg2 and AMPKg3, It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways, The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, The human AMPKg1 gene encodes a 331 amino acid protein, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation, respectively, respectively, respectively, which are 569 and 492 amino acid proteins, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
AMPK AMPKa2 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
AMPK gamma 1/2/3 Conjugated |
| Short name: |
Conjugated, AMPK gamma 1/2/3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, AMPK g 1/2/3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9377 |
| Gene: |
PRKAA2 |
More about : PRKAA2 |
| Long gene name: |
protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene: |
PRKAA |
| Synonyms gene name: |
AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Locus: |
1p32, 2 |
| Discovery year: |
1995-12-12 |
| GenBank acession: |
BC069823 |
| Entrez gene record: |
5563 |
| Pubmed identfication: |
7959015 |
| RefSeq identity: |
NM_006252 |
| Havana BLAST/BLAT: |
OTTHUMG00000008282 |