| Long name: |
ALEXA FLUOR 647 Conjugated, MTA2 Polyclonal Antibody |
| Also known as: |
Anti-MTA2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MTA2 |
| Specificity: |
This is a highly specific antibody against MTA2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTA2 |
| Gene ID Number: |
9219 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A similar protein, Elevation of MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, MTA1 contains a single SH3-binding motif and a zinc finger domain, MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin, MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis, MTA2, Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, Structurally, along with a region similar to the co-repressor protein N-Cor, also designated MTA1-L1 (MTA1-like protein 1), and therefore may be an indicator for assessing the potential malignancies of various tumors, gastrointestinal and breast carcinomas, increase mammary cell motility and potentiate growth, shares more than 55% sequence homology with MTA1 and is ubiquitously expressed, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity, MTA1 is a component of the NURD (nucleosome remodeling and histone deacetylation) complex |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MTA1-L1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MTA2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MTA2 |
| Short name: |
MTA2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, MTA2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7411 |
| Gene: |
MTA2 |
More about : MTA2 |
| Long gene name: |
metastasis associated 1 family member 2 |
| Synonyms gene: |
MTA1L1 |
| Synonyms gene name: |
member 2 , metastasis associated gene family |
| Locus: |
11q12, 3 |
| Discovery year: |
1999-05-17 |
| GenBank acession: |
AB016591 |
| Entrez gene record: |
9219 |
| Pubmed identfication: |
9929979 |
| RefSeq identity: |
NM_004739 |
| Classification: |
GATA zinc finger domain containing NuRD complex Myb/SANT domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000167684 |