| Long name: |
MTA2 Primary Polyclonal Antibody |
| Also known as: |
MTA2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MTA2 |
| Specificity: |
This is a highly specific antibody against MTA2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTA2 |
| Gene ID number: |
9219 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A similar protein, Elevation of MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, MTA1 contains a single SH3-binding motif and a zinc finger domain, MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin, MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis, MTA2, Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, Structurally, along with a region similar to the co-repressor protein N-Cor, also designated MTA1-L1 (MTA1-like protein 1), and therefore may be an indicator for assessing the potential malignancies of various tumors, gastrointestinal and breast carcinomas, increase mammary cell motility and potentiate growth, shares more than 55% sequence homology with MTA1 and is ubiquitously expressed, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity, MTA1 is a component of the NURD (nucleosome remodeling and histone deacetylation) complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MTA1 L1 protein, MTA1-L1 protein, MTA1L1, MTA1L1: metastasis-associated 1-like 1, MTA2_HUMAN, Metastasis associated 1 family member 2, Metastasis associated 1 like 1, Metastasis associated gene 1 like 1, Metastasis associated gene family member 2, Metastasis associated protein 2, Metastasis associated protein MTA 2, Metastasis associated protein MTA2, Mmta2, P53 target protein in deacetylase complex, PID, Mata1l1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MTA2 |
| Short name: |
MTA2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MTA2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7411 |
| Gene: |
MTA2 |
More about : MTA2 |
| Long gene name: |
metastasis associated 1 family member 2 |
| Synonyms gene: |
MTA1L1 |
| Synonyms gene name: |
member 2 , metastasis associated gene family |
| Synonyms: |
MTA1-L1 |
| Locus: |
11q12, 3 |
| Discovery year: |
1999-05-17 |
| GenBank acession: |
AB016591 |
| Entrez gene record: |
9219 |
| Pubmed identfication: |
9929979 |
| RefSeq identity: |
NM_004739 |
| Classification: |
GATA zinc finger domain containing NuRD complex Myb/SANT domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000167684 |