| Long name: |
ALEXA FLUOR 647 Conjugated, Tal1 Polyclonal Antibody |
| Also known as: |
Anti-Tal1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tal1 |
| Specificity: |
This is a highly specific antibody against Tal1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tal1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In addition, TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis, This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, making it the most frequent gain-of-function mutation observed in this disorder, Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MCPH7 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Tal1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Tal1 |
| Short name: |
Tal1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, T-cell acute lymphocytic leukemia 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10879 |
| Gene: |
STIL |
More about : STIL |
| Long gene name: |
SCL/TAL1 interrupting locus |
| Synonyms gene: |
SIL |
| Synonyms gene name: |
TAL1 (SCL) interrupting locus |
| Locus: |
1p33 |
| Discovery year: |
1997-11-05 |
| GenBank acession: |
M74558 |
| Entrez gene record: |
6491 |
| Pubmed identfication: |
2209547 |
| RefSeq identity: |
NM_003035 |
| Havana BLAST/BLAT: |
OTTHUMG00000007851 |