| Long name: |
ALEXA FLUOR 594 Conjugated, Tal1 Polyclonal Antibody |
| Also known as: |
Anti-Tal1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tal1 |
| Specificity: |
This is a highly specific antibody against Tal1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tal1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In addition, TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis, This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, making it the most frequent gain-of-function mutation observed in this disorder, Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MCPH7 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Tal1 |
| Short name: |
Tal1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, T-cell acute lymphocytic leukemia 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10879 |
| Gene: |
STIL |
More about : STIL |
| Long gene name: |
SCL/TAL1 interrupting locus |
| Synonyms gene: |
SIL |
| Synonyms gene name: |
TAL1 (SCL) interrupting locus |
| Locus: |
1p33 |
| Discovery year: |
1997-11-05 |
| GenBank acession: |
M74558 |
| Entrez gene record: |
6491 |
| Pubmed identfication: |
2209547 |
| RefSeq identity: |
NM_003035 |
| Havana BLAST/BLAT: |
OTTHUMG00000007851 |