| Long name: |
FITC Conjugated, PSMD6 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PSMD6 |
| Specificity: |
This is a highly specific antibody against PSMD6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PSMD6/Proteasome regulatory particle subunit p44S10 |
| Gene ID number: |
9861 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
451Lu and WM164, At specific stages of development, In addition to normal tissue expression, Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, The pUb-R2 subunit, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5), is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells, liver, originally identified as S5a, p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, p44S10 is also expressed in several melanoma cell lines, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation in vivo, selective breakdown of cellular proteins is ensured by two distinct pathways, skeletal muscle and pancreas, such as MCF-7, ubiquitination and degradation by the 26S proteasome, In eukaryotic cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
S10 p44S10 KIAA0107 Rpn7 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PSMD6 Conjugated |
| Short name: |
FITC Conjugated, PSMD6 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
6 (Antibody to), fluorecein coupled, macropain) 26S subunit, non-ATPase, proteasome (prosome |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
6, ATPase activity, BT, PSMD6 and IDBG-43018 and ENSG00000163636 and 9861, Psmd6 and IDBG-132715 and ENSMUSG00000021737 and 66413, TAP-dependent and biological process this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, macropain) 26S subunit, non-ATPase, nuclei, p42A and p44S10 and Rpn7 and S10 and SGA-113M, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0016887 and ATPase activity and molecular function this GO :0022624 and proteasome accessory complex and cellular component this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0016887 : ATPase activity, this GO :0016887 : ATPase activity, 88479 and IDBG-645134 and ENSBTAG00000015112 and 538625, proteasome (prosome |
| Identity: |
9564 |
| Gene: |
PSMD6 |
More about : PSMD6 |
| Long gene name: |
non-ATPase 6 , proteasome 26S subunit |
| Synonyms gene name: |
6 , macropain) 26S subunit, non-ATPase, proteasome (prosome |
| Locus: |
3p14, 1 |
| Discovery year: |
1995-12-06 |
| GenBank acession: |
AF215935 |
| Entrez gene record: |
9861 |
| Pubmed identfication: |
10723133 |
| RefSeq identity: |
NM_014814 |
| Classification: |
Proteasome |
| Havana BLAST/BLAT: |
OTTHUMG00000158765 |