| Long name: |
RNF158 Primary Polyclonal Antibody |
| Also known as: |
RNF158 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RNF158 |
| Specificity: |
This is a highly specific antibody against RNF158 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF158 |
| Gene ID number: |
153769 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Due to alternative splicing events, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, SH3RF2 (SH3 domain containing ring finger 2), SH3RF2 binds an E2 ubiquitin-conjugating enzyme, SH3RF2 is expressed as two different isoforms, This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation, Via its RING-type zinc finger domain, also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HEPP1, Putative E3 ubiquitin protein ligase SH3RF2, Putative E3 ubiquitin-protein ligase SH3RF2, RING finger protein 158, SH3 domain containing RING finger protein 2, SH3 domain-containing RING finger protein 2, SH3R2_HUMAN, Sh3rf2, Heart protein phosphatase 1-binding protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RNF158 |
| Short name: |
RNF158 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RNF158 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
26299 |
| Gene: |
SH3RF2 |
More about : SH3RF2 |
| Long gene name: |
SH3 domain containing ring finger 2 |
| Synonyms gene: |
PPP1R39 |
| Synonyms gene name: |
protein phosphatase 1, regulatory subunit 39 |
| Synonyms: |
FLJ23654 RNF158 Hepp1 POSHER |
| Synonyms name: |
heart protein phosphatase 1-binding protein POSH-eliminating RING protein |
| Locus: |
5q32 |
| Discovery year: |
2004-03-05 |
| GenBank acession: |
AL833297 |
| Entrez gene record: |
153769 |
| Pubmed identfication: |
22128169 |
| RefSeq identity: |
NM_152550 |
| Classification: |
Ring finger proteins Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000129685 |