| Long name: |
ALEXA FLUOR 350 Conjugated, CDK5RAP2 Polyclonal Antibody |
| Also known as: |
Anti-CDK5RAP2 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CDK5RAP2 |
| Specificity: |
This is a highly specific antibody against CDK5RAP2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDK5RAP2 |
| Gene ID Number: |
55755 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity, CDK5RAP2, CDK5RAP2 associates with centrosomes throughout the cell cycle, Expressed in placenta, Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events, also known as Centrosome-associated protein 215, brain and kidney, brain weight and significant neurological deficits, heart, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1, liver, lung, pancreas, skeletal muscle, which is characterized by markedly reduced head size, Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
C48 FLJ10867 CEP215 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
CDK5RAP2 |
| Short name: |
CDK5RAP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, CDK5RAP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18672 |
| Gene: |
CDK5RAP2 |
More about : CDK5RAP2 |
| Long gene name: |
CDK5 regulatory subunit associated protein 2 |
| Synonyms gene: |
MCPH3 |
| Synonyms gene name: |
microcephaly, primary autosomal recessive 3 |
| Synonyms name: |
centrosomin |
| Locus: |
9q33, 2 |
| Discovery year: |
2002-07-22 |
| GenBank acession: |
BK005504 |
| Entrez gene record: |
55755 |
| Pubmed identfication: |
10721722 17764569 24466316 |
| RefSeq identity: |
NM_018249 |
| Havana BLAST/BLAT: |
OTTHUMG00000021043 |