| Long name: |
FITC Conjugated, DVL2 (Thr224) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DVL2 Thr224 |
| Specificity: |
This antibody will recognize DVL3 when phosphorylated at Thr205, This is a highly specific antibody against DVL2 Thr224 |
| Modification: |
Phosphorylation |
| Modification site: |
Thr224 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
200-250/736 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224 |
| Gene ID number: |
1856 |
| Swiss Prot: |
O14641 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Plays a role both in canonical and non-canonical Wnt signaling, Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity), Promotes internalization and degradation of frizzled proteins upon Wnt signaling, Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DVL2 (Thr224) Conjugated |
| Short name: |
FITC Conjugated, DVL2 (Thr224) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DVL2 (Thr224) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3086 |
| Gene: |
DVL2 |
More about : DVL2 |
| Long gene name: |
dishevelled segment polarity protein 2 |
| Synonyms gene name: |
dishevelled 2 (homologous to Drosophila dsh) dishevelled, dsh homolog 2 (Drosophila) |
| Locus: |
17p13, 1 |
| Discovery year: |
1996-03-12 |
| GenBank acession: |
BC014844 |
| Entrez gene record: |
1856 |
| Pubmed identfication: |
8662242 |
| RefSeq identity: |
NM_004422 |
| Classification: |
Dishevelled segment polarity proteins PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000102155 |