| Long name: |
ALEXA FLUOR 488 Conjugated, TRPM8 Polyclonal Antibody |
| Also known as: |
Anti-TRPM8 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRPM8 |
| Specificity: |
This is a highly specific antibody against TRPM8 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPM8 |
| Gene ID Number: |
79054 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activated by icilin, Activated upon depolarization, Involved in menthol sensation, Permeable for monovalent cations sodium, Temperature sensing is tightly linked to voltage-dependent gating, Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing, The chemical agonists menthol functions as a gating modifier, and cesium and divalent cation calcium, by being activated by cold temperature below 25 degrees Celsius, changes in temperature resulting in graded shifts of its voltage-dependent activation curves, cold and modulation of intracellular pH, eucalyptol, menthol, potassium, shifting activation curves towards physiological membrane potentials, Receptor-activated non-selective cation channel involved in detection of sensations such as coolness |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TRPM8 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TRPM8 |
| Short name: |
TRPM8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, TRPM8 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17961 |
| Gene: |
TRPM8 |
More about : TRPM8 |
| Long gene name: |
transient receptor potential cation channel subfamily M member 8 |
| Synonyms gene name: |
member 8 , subfamily M, transient receptor potential cation channel |
| Locus: |
2q37, 1 |
| Discovery year: |
2002-01-11 |
| GenBank acession: |
AC005538 |
| Entrez gene record: |
79054 |
| Pubmed identfication: |
16382100 |
| RefSeq identity: |
NM_024080 |
| Classification: |
Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000059129 |