| Long name: |
ALEXA FLUOR 488 Conjugated, TRPM7 Polyclonal Antibody |
| Also known as: |
Anti-TRPM7 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRPM7 |
| Specificity: |
This is a highly specific antibody against TRPM7 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
800-850/1865 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPM7 |
| Gene ID Number: |
54822 |
| Swiss Prot: |
Q96QT4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Divalent cation channel permeable to calcium and magnesium, Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death, Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx, May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell, Phosphorylates annexin A1 (ANXA1), The kinase activity is essential for the channel function, Essential ion channel and serine/threonine-protein kinase |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CHAK1 LTRPC7 TRP-PLIK |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TRPM7 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TRPM7 |
| Short name: |
TRPM7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, member 7 (Antibody to), subfamily M, transient receptor potential cation channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TRPM7 and IDBG-11807 and ENSG00000092439 and 54822, TRPM7 and IDBG-646663 and ENSBTAG00000031165 and 514642, Trpm7 and IDBG-204376 and ENSMUSG00000027365 and 58800, member 7, subfamily M, this GO :0001726 and ruffle and cellular component this GO :0003779 and actin binding and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0005216 and ion channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016340 and calcium-dependent cell-matrix adhesion and biological process this GO :0016772 and transferase activity, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0005216 : ion channel activity and also this GO :0005262 : calcium channel activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0005216 : ion channel activity, this GO :0005262 : calcium channel activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0017022 : myosin binding, this GO :0046872 : metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017022 : myosin binding and also this GO :0046872 : metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0017022 and myosin binding and molecular function this GO :0031032 and actomyosin structure organization and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0055085 and transmembrane transport and biological process this GO :0070266 and necroptotic process and biological process this GO :0070588 and calcium ion transmembrane transport and biological process, transient receptor potential cation channel |
| Identity: |
17994 |
| Gene: |
TRPM7 |
More about : TRPM7 |
| Long gene name: |
transient receptor potential cation channel subfamily M member 7 |
| Synonyms gene name: |
member 7 , subfamily M, transient receptor potential cation channel |
| Locus: |
15q21, 2 |
| Discovery year: |
2002-01-11 |
| GenBank acession: |
AF346629 |
| Entrez gene record: |
54822 |
| Pubmed identfication: |
11161216 11385574 16382100 |
| RefSeq identity: |
NM_017672 |
| Classification: |
Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000172449 |