| Long name: |
CECR1 Primary Polyclonal Antibody |
| Also known as: |
CECR1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CECR1 |
| Specificity: |
This is a highly specific antibody against CECR1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CECR1/ADGF |
| Gene ID number: |
51816 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified, Adenosine deaminase degrades extracellular adenosine, CECR family members are widely expressed, CECR1 has the highest expression in adult heart, CECR2, CECR2 is also involved in neurulation and chromatin remodeling, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9, CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, It is a candidate gene for cat eye syndrome, It may act as a growth factor and have adenosine deaminase activity, Mutations in the CECR2 gene result in neural tube defects, Specifically, The cat eye syndrome critical region protein (CECR) family includes CECR1, The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), Two transcript variants encoding distinct isoforms have been identified for this gene, a developmental disorder associated with the duplication of a 2 Mb region of 22q11, although in some tissues it is associated with adenosine deaminase-binding protein, and normal or near-normal mental development, downslanting palpebral fissures, frequent occurrence of heart and renal malformations, lung, lymphoblasts and placenta, preauricular tags and/or pits, which is toxic for lymphocytes, 2, Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, CECR1 is a member of the adenosine and AMP deaminases family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CECR 1, CECR1_HUMAN, Cat eye syndrome chromosome region candidate 1, Cat eye syndrome critical region protein 1, Cat eye syndrome critical region protein 1 precursor, IDGFL, ADGF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CECR1 |
| Short name: |
CECR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
candidate 1 (Antibody to), catalase eye syndrome chromosome region |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CECR1 and IDBG-641275 and ENSBTAG00000017313 and 617805, CECR1 and IDBG-933 and ENSG00000093072 and 51816, Extracellular, candidate 1, proteoglycan binding, this GO :0004000 and adenosine deaminase activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006154 and adenosine catabolic process and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008152 and metabolic process and biological process this GO :0008201 and heparin binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0019239 and deaminase activity and molecular function this GO :0031685 and adenosine receptor binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043103 and hypoxanthine salvage and biological process this GO :0043394 and proteoglycan binding and molecular function this GO :0046103 and inosine biosynthetic process and biological process, this GO :0004000 : adenosine deaminase activity, this GO :0004000 : adenosine deaminase activity and also this GO :0008083 : growth factor activity and also this GO :0008201 : heparin binding and also this GO :0008270 : zinc ion binding and also this GO :0019239 : deaminase activity and also this GO :0031685 : adenosine receptor binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043394 : proteoglycan binding, this GO :0008083 : growth factor activity, this GO :0008201 : heparin binding, this GO :0008270 : zinc ion binding, this GO :0019239 : deaminase activity, this GO :0031685 : adenosine receptor binding, this GO :0042803 : protein homodimerization activity, this GO :0043394 : proteoglycan binding, cat eye syndrome chromosome region |
| Identity: |
1839 |
| Gene: |
ADA2 |
More about : ADA2 |
| Long gene name: |
adenosine deaminase 2 |
| Synonyms gene: |
IDGFL CECR1 |
| Synonyms gene name: |
candidate 1 , cat eye syndrome chromosome region |
| Synonyms: |
ADGF |
| Locus: |
22q11, 1 |
| Discovery year: |
1999-12-09 |
| GenBank acession: |
AF190746 |
| Entrez gene record: |
51816 |
| Pubmed identfication: |
10756095 27663683 |
| Classification: |
Adenosine deaminase family |
| Havana BLAST/BLAT: |
OTTHUMG00000030726 |