| Long name: |
Biotin Conjugated, LGR6 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LGR6 |
| Specificity: |
This is a highly specific antibody against LGR6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
430-480/967 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human LGR6 |
| Gene ID number: |
59352 |
| Swiss Prot: |
Q9HBX8 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In contrast to classical G-protein coupled receptors, May act as a tumor suppressor, RSPO2, RSPO3 or RSPO4), Upon binding to R-spondins (RSPO1, associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, does not activate heterotrimeric G-proteins to transduce the signal, triggering the canonical Wnt signaling pathway to increase expression of target genes, Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
FLJ14471 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LGR6 Conjugated |
| Short name: |
Conjugated, LGR6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, LGR6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19719 |
| Gene: |
LGR6 |
More about : LGR6 |
| Long gene name: |
leucine rich repeat containing G protein-coupled receptor 6 |
| Locus: |
1q32, 1 |
| Discovery year: |
2003-12-04 |
| GenBank acession: |
AF190501 |
| Entrez gene record: |
59352 |
| Pubmed identfication: |
10935549 |
| RefSeq identity: |
NM_021636 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000041383 |