| Long name: |
HOXD9 Primary Polyclonal Antibody |
| Also known as: |
HOXD9 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HOXD9 |
| Specificity: |
This is a highly specific antibody against HOXD9 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HOXD9 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activation of HoxD9 depends on the structure of the target regulatory element, Furthermore, HoxD9 may be a multifunctional transcriptional regulator, HoxD9 transcripts are also detected in the synovial tissue of arthritic mice, In vivo, Specifically, The HoxD9 protein is expressed in the early stages of mouse joint development, The human HoxD9 protein is also differentially expressed in the human cervical cancer cell line HeLa, and results in differential cofactor interaction, as it contains different activation domains, but is not expressed in the normal cervix and may thus play a role in tumorigenesis, but not in osteoarthritis patients, but not in that of normal mice, primarily in the articular cartilage, suggesting that HoxD9 may have a role in the pathology of arthritis, the HoxD9 protein interacts with the autoregulatory and cross-regulatory enhancers of the murine HoxB1 and human HoxD9 genes, the HoxD9 protein interacts with the human control region (HCR) of the HoxD9 gene, the HoxD9 protein is highly expressed in the synoviocytes of patients with rheumatoid arthritis (RA), thus inducing transcription of the HoxD9 promoter, The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HOX4, HOX4C, HXD9_HUMAN, Homeobox protein Hox D9, Hox 4, Hox 5, RP23 313J15, 2, 3, 10, homeobox D9 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HOXD9 |
| Short name: |
HOXD9 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HOXD9 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5140 |
| Gene: |
HOXD9 |
More about : HOXD9 |
| Long gene name: |
homeobox D9 |
| Synonyms gene: |
HOX4C HOX4 |
| Synonyms gene name: |
homeo box D9 |
| Locus: |
2q31, 1 |
| Discovery year: |
1990-06-15 |
| Entrez gene record: |
3235 |
| Pubmed identfication: |
1973146 1358459 |
| Classification: |
HOXL subclass homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000132516 |