| Long name: |
Biotin Conjugated, GPR120 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR120 |
| Specificity: |
This is a highly specific antibody against GPR120 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human G protein coupled receptor 120 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Consequently, FFAs act as signaling molecules and are an important energy source, GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying, GLP-1 belongs to the class of molecules known as the incretins, GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids), One such response occurs when dietary FFAs stimulate GPR120, They also employ various physiological responses through their GPCRs, This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes, which are associated with insulin secreted from the pancreas as a result of food intake, GPR120 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PGR4 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPR120 Conjugated |
| Short name: |
Conjugated, GPR120 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GPR120 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19061 |
| Gene: |
FFAR4 |
More about : FFAR4 |
| Long gene name: |
free fatty acid receptor 4 |
| Synonyms gene: |
GPR129 GPR120 O3FAR1 |
| Synonyms gene name: |
G protein-coupled receptor 129 G protein-coupled receptor 120 omega-3 fatty acid receptor 1 |
| Locus: |
10q23, 33 |
| Discovery year: |
2003-08-22 |
| Entrez gene record: |
338557 |
| Pubmed identfication: |
20471368 19723586 15619630 20813258 |
| RefSeq identity: |
NM_181745 |
| Classification: |
Free fatty acid receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000034409 |