| Long name: |
UGCG Primary Polyclonal Antibody |
| Also known as: |
UGCG PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
UGCG |
| Specificity: |
This is a highly specific antibody against UGCG |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UGCG |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Glucosylceramide synthase catalyzes the first glycosylation step in glycosphingolipid biosynthesis and functions as a glucosyltransferase and flippase in the transfer of glucose to ceramide, Glucosylceramide synthase operates in cell recognition, It is a widely expressed integral membrane protein encoded by UGCG, The enzyme can be found in the plasma membrane of all eukaryotic cells, The regulation of ceramide levels through glucosylceramide synthase has been associated with the induction of apoptosis and notable research implicates this relationship with drug-induced apoptosis in a variety of cell types, also designated ceramide glucosyltransferase, and a significant concentration of glucosylceramide synthase activity has been reported in the Golgi complex, belongs to the glycosyltransferase 2 family, cell proliferation and differentiation, immune recognition and signal transduction, Glucosylceramide synthase (GCS) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Ceramide glucosyltransferase, GCS, GLCT 1, GLCT-1, GLCT1, Glucosylceramide synthase, UDP glucose N acylsphingosine D glucosyltransferase, UDP glucose ceramide glucosyltransferase, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, Ugcg, CEGT_HUMAN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
UGCG |
| Short name: |
UGCG Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
UGCG (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12524 |
| Gene: |
UGCG |
More about : UGCG |
| Long gene name: |
UDP-glucose ceramide glucosyltransferase |
| Synonyms: |
GCS |
| Synonyms name: |
glucosylceramide synthase ceramide glucosyltransferase |
| Locus: |
9q31, 3 |
| Discovery year: |
1997-08-28 |
| GenBank acession: |
D50840 |
| Entrez gene record: |
7357 |
| Pubmed identfication: |
8643456 9605861 |
| RefSeq identity: |
NM_003358 |
| Classification: |
UDP-glucose ceramide glucosyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000020498 |