| DNA lentivector for transduction information: |
GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions, Vectors with selection markers like kanamycin, our 3rd Generation Packaging mixture, pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C, puromycin or cumate are available, Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
CFLAR Lentiviral Vector (CMV) (pLenti-GIII-CMV) |
| Short name: |
CFLAR Lentiviral Vector ( ) (CMV) (pLenti-GIII-CMV) |
| Technique: |
Vectors |
| Species: |
Humans, Human |
| Alternative name: |
member 6) (TNFRSF6)-associated via death domain-like apoptosis regulator Lentiviral integrating Desoxyribonucleic acid sequence (H, sapiens) (cytomegalovirus) (pLenti-GIII-cytomegalovirus), CASP8 and Fas (TNF receptor superfamily |
| Alternative to gene target: |
CFLAR and IDBG-78386 and ENSG00000003402 and 8837, FLIP and IDBG-643202 and ENSBTAG00000010998 and 497199, Plasma membranes, c-FLIP and c-FLIPL and c-FLIPR and c-FLIPS and CASH and CASP8AP1 and Casper and CLARP and FLAME and FLAME-1 and FLAME1 and FLIP and I-FLICE and MRIT, death effector domain binding, this GO :0002020 and protease binding and molecular function this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005123 and death receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0014732 and skeletal muscle atrophy and biological process this GO :0014842 and regulation of satellite cell proliferation and biological process this GO :0014866 and skeletal myofibril assembly and biological process this GO :0016032 and viral process and biological process this GO :0031264 and death-inducing signaling complex and cellular component this GO :0031265 and CD95 death-inducing signaling complex and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0035877 and death effector domain binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0060544 and regulation of necroptotic process and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097342 and ripoptosome and cellular component this GO :1901740 and negative regulation of myoblast fusion and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005123 : death receptor binding and also this GO :0005515 : protein binding and also this GO :0008047 : enzyme activator activity and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0032403 : protein complex binding and also this GO :0035877 : death effector domain binding, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0005123 : death receptor binding, this GO :0005515 : protein binding, this GO :0008047 : enzyme activator activity, this GO :0008234 : cysteine-type peptidase activity, this GO :0032403 : protein complex binding, this GO :0035877 : death effector domain binding, CASP8 and FADD-like apoptosis regulator |
| Identity: |
1876 |
| Gene: |
CFLAR |
More about : CFLAR |
| Long gene name: |
CASP8 and FADD like apoptosis regulator |
| Synonyms gene: |
CASP8AP1 |
| Synonyms gene name: |
CASP8 and FADD-like apoptosis regulator |
| Synonyms: |
CASH Casper CLARP FLAME FLIP I-FLICE MRIT c-FLIP |
| Locus: |
2q33, 1 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
AF005774 |
| Entrez gene record: |
8837 |
| Pubmed identfication: |
9208847 9217161 |
| RefSeq identity: |
NM_003879 |
| Classification: |
Endogenous ligands Death effector domain containing Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000132819 |