| Long name: |
FITC Conjugated, OLIG1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OLIG1 |
| Specificity: |
This is a highly specific antibody against OLIG1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human OLIG1 |
| Gene ID number: |
116448 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
OLIG proteins are candidates for molecular markers of human glial brain tumors, OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas, OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis, OLIG1 and OLIG2 interact with the Nkx-2, OLIG2 is more widely expressed in embryonic brain than OLIG1, Therefore, These interactions between OLIG proteins and Nkx-2, which are the most common primary malignancies of the human brain, which differ in tissue expression, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube, while OLIG3 is primarily expressed in non-neural tissues, 2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development, 2 homeodomain protein, The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
BHLHB6 bHLHe21 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OLIG1 Conjugated |
| Short name: |
FITC Conjugated, OLIG1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, OLIG1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16983 |
| Gene: |
OLIG1 |
More about : OLIG1 |
| Long gene name: |
oligodendrocyte transcription factor 1 |
| Synonyms name: |
6 , class B, helix-loop-helix protein, oligodendrocyte-specific bHLH transcription factor 1 oligodendrocyte lineage transcription factor 1 basic domain |
| Locus: |
21q22, 11 |
| Discovery year: |
2001-12-04 |
| GenBank acession: |
AP000109 |
| Entrez gene record: |
116448 |
| Pubmed identfication: |
11526205 |
| RefSeq identity: |
NM_138983 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000065064 |