| Long name: |
Biotin Conjugated, caspase-9 p10 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
caspase-9 p10 |
| Specificity: |
This is a highly specific antibody against caspase-9 p10 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
393-416/416 |
| Subcellular location: |
Mitochondrion, Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human caspase-9 subunit p10 |
| Gene ID number: |
842 |
| Swiss Prot: |
P55211 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3, Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9, Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, Proteolytically cleaves poly(ADP-ribose) polymerase (PARP), Involved in the activation cascade of caspases responsible for apoptosis execution |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, Caspase-9, ICE-LAP6, ICE-like apoptotic protease 6, PPP1R56, MCH6 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Description: |
CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways, Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation |
| Gene target: |
caspase-9 p10 Conjugated |
| Short name: |
Conjugated, caspase-9 p10 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, caspase-9 p10 (Antibody to) |
| Alternative technique: |
antibodies |