| Long name: |
SHFM3 Primary Polyclonal Antibody |
| Also known as: |
SHFM3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SHFM3 |
| Specificity: |
This is a highly specific antibody against SHFM3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHFM3 |
| Gene ID number: |
6468 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Likely to be involved in key signaling pathways crucial for normal limb development, May participate in Wnt signaling, SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits, Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) , Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Dactylin, F box and WD 40 domain containing protein 4, F box and WD 40 domain protein 4, F box and WD repeat domain containing 4, F box/WD repeat containing protein 4, F box/WD repeat protein 4, F-box and WD-40 domain-containing protein 4, F-box/WD repeat-containing protein 4, FBW 4, FBW4, FBWD 4, FBWD4, FBXW 4, FBXW4, FBXW4_HUMAN, SHFM 3, SHSF 3, SHSF3, Split hand/foot malformation ectrodactyly type, DAC |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SHFM3 |
| Short name: |
SHFM3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SHFM3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10847 |
| Gene: |
FBXW4 |
More about : FBXW4 |
| Long gene name: |
F-box and WD repeat domain containing 4 |
| Synonyms gene: |
SHFM3 |
| Synonyms gene name: |
split hand/foot malformation (ectrodactyly) type 3 F-box and WD-40 domain protein 4 |
| Synonyms: |
Fbw4 dactylin |
| Locus: |
10q24, 32 |
| Discovery year: |
1994-09-26 |
| GenBank acession: |
AF281859 |
| Entrez gene record: |
6468 |
| Pubmed identfication: |
8723077 7912888 |
| RefSeq identity: |
NM_022039 |
| Classification: |
F-box and WD repeat domain containing WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000018938 |