| Long name: |
Ube2L6 Primary Polyclonal Antibody |
| Also known as: |
Ube2L6 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Ube2L6 |
| Specificity: |
This is a highly specific antibody against Ube2L6 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ube2L6 |
| Gene ID number: |
9246 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Like other E2 enzymes, Parkin shares sequence homology with other UBC8 binding proteins such as HHARI and H7-AP1, The primary function of ubiquitin in mammalian systems is to clear abnormal, UBC8 binds to the human homolog of Drosophila ariadne (HHARI) and UBC7-associated protein (H7-AP1) as well as double ring-finger protein (Dorfin), UBC8 forms a thioester bond with ubiquitin in an E1-dependent manner, UBC8 is enriched in the central nervous system and interacts with Parkin, Ubiquitin conjugating enzyme 8 (UBC8) is an E2 enzyme involved in the ubiquitin pathway for protein degradation, a RING-finger-containing protein implicated in the pathogenesis of familial Parkinsonâ, and improperly folded proteins by targeting them for proteosome degradation, either free or covalently attached to cellular proteins, foreign, highly conserved protein found in all eukaryotic cells, &euro, &trade, Ubiquitin is an abundant, s disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
RIG B, RIG-B, Retinoic acid-induced gene B protein, UB2L6_HUMAN, UBCH 8, UBCH8, UBE2L6, Ubiquitin carrier protein, Ubiquitin carrier protein L6, Ubiquitin conjugating enzyme E2L 6, Ubiquitin protein ligase, Ubiquitin protein ligase L6, Ubiquitin-protein ligase L6, Ubiquitin/ISG15 conjugating enzyme E2 L6, Ubiquitin/ISG15-conjugating enzyme E2 L6, Retinoic acid induced gene B protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Ube2L6 |
| Short name: |
Ube2L6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Ube2L6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12490 |
| Gene: |
UBE2L6 |
More about : UBE2L6 |
| Long gene name: |
ubiquitin conjugating enzyme E2 L6 |
| Synonyms gene name: |
ubiquitin-conjugating enzyme E2L 6 |
| Synonyms: |
UBCH8 |
| Locus: |
11q12, 1 |
| Discovery year: |
1999-02-26 |
| GenBank acession: |
AF031141 AK093462 BC032491 |
| Entrez gene record: |
9246 |
| Pubmed identfication: |
9153201 |
| RefSeq identity: |
NM_004223 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000167047 |