| Long name: |
LRRC59 Primary Polyclonal Antibody |
| Also known as: |
LRRC59 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
LRRC59 |
| Specificity: |
This is a highly specific antibody against LRRC59 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LRRC59 |
| Gene ID number: |
55379 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
BRCA1 is directly involved in DNA repair, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene encoding LRRC59 maps to human chromosome 17, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, also known as PRO1855, colon, is a 307 amino acid protein that contains leucine-rich repeats and may play a role in protein binding events throughout the cell, namely, p53 and BRCA1, prostate gland and fallopian tubes, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, LRRC59 (leucine rich repeat containing 59) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
LRC59_HUMAN, LRRC59, PRO1855, Leucine-rich repeat-containing protein 59 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LRRC59 |
| Short name: |
LRRC59 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
LRRC59 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28817 |
| Gene: |
LRRC59 |
More about : LRRC59 |
| Long gene name: |
leucine rich repeat containing 59 |
| Synonyms: |
PRO1855 FLJ21675 |
| Locus: |
17q21, 33 |
| Discovery year: |
2006-01-12 |
| GenBank acession: |
AK025328 |
| Entrez gene record: |
55379 |
| Pubmed identfication: |
12477932 |
| RefSeq identity: |
NM_018509 |
| Havana BLAST/BLAT: |
OTTHUMG00000162079 |