| Long name: |
ALEXA FLUOR 488 Conjugated, UBE2E2 Polyclonal Antibody |
| Also known as: |
Anti-UBE2E2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
UBE2E2 |
| Specificity: |
This is a highly specific antibody against UBE2E2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UBE2E2 |
| Gene ID Number: |
7325 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A wide range of enzymes facilitate this proteolytic ubiquitin pathway, The E3 enzyme then catalyzes the transfer of ubiquitin from E2 to the appropriate protein substrate, The first step in the ubiquitination process requires the ATP-dependent activation of the ubiquitin C-terminus and the assembly of multi-ubiquitin chains by the E1 enzyme, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), The ubiquitin chain is then conjugated to the E2 enzyme to generate an intermediate ubiquitin-E2 complex, one of which is UBE2E2 (also known as UBCH8 in human), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), thereby playing an important role in protein degradation, thereby targeting that substrate for degradation, which functions as an E2 enzyme and catalyzes the ATP-dependent covalent attachment of ubiquitin to target proteins, Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
UbcH8 FLJ25157 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the UBE2E2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
UBE2E2 |
| Short name: |
UBE2E2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, UBE2E2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12478 |
| Gene: |
UBE2E2 |
More about : UBE2E2 |
| Long gene name: |
ubiquitin conjugating enzyme E2 E2 |
| Synonyms gene name: |
ubiquitin-conjugating enzyme E2E 2 (homologous to yeast UBC4/5) ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) ubiquitin-conjugating enzyme E2E 2 |
| Locus: |
3p24, 3 |
| Discovery year: |
1997-12-15 |
| GenBank acession: |
AK057886 |
| Entrez gene record: |
7325 |
| Pubmed identfication: |
9371400 |
| RefSeq identity: |
NM_152653 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000130482 |