| Long name: |
Cy5, 5 Conjugated, G protein beta subunit like Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
G protein beta subunit like |
| Specificity: |
This is a highly specific antibody against G protein beta subunit like |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human G protein beta subunit like |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis, Amino-acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases, Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, heart and kidney, mTORC1 is activated in response to growth factors or amino-acids, mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E), mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation, with highest levels in skeletal muscle, Subunit of both mTORC1 and mTORC2, Tissue specificity:Broadly expressed |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
G protein beta subunit-like, GBL, GBL protein, Gable, LST8_HUMAN, MGC111011, Mammalian lethal with SEC13 protein 8, Protein GbetaL, TORC subunit LST8, Target of rapamycin complex subunit LST8, mLST8, G protein beta subunit like |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
G protein beta subunit like Conjugated |
| Short name: |
Conjugated, G protein beta subunit like Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, G protein b functionnal sequence like (Antibody to) |
| Alternative technique: |
antibodies |