| Long name: |
KLHL21 Primary Polyclonal Antibody |
| Also known as: |
KLHL21 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
KLHL21 |
| Specificity: |
This is a highly specific antibody against KLHL21 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLHL21 |
| Gene ID number: |
9903 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB, Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome, Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
KIAA0469, KLH21_HUMAN, KLHL21, MGC99635, Kelch like protein 21 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
KLHL21 |
| Short name: |
KLHL21 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
kelch-like 21 (Drosophila) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Cytoplasm, KLHL21 and IDBG-88014 and ENSG00000162413 and 9903, Klhl21 and IDBG-206190 and ENSMUSG00000073700 and 242785, protein binding, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005827 and polar microtubule and cellular component this GO :0007067 and mitotic nuclear division and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0031463 and Cul3-RING ubiquitin ligase complex and cellular component this GO :0032465 and regulation of cytokinesis and biological process this GO :0035853 and chromosome passenger complex localization to spindle midzone and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 51832 and IDBG-633762 and ENSBTAG00000008350 and 506632, kelch-like 21 (Drosophila) |
| Identity: |
29041 |
| Gene: |
KLHL21 |
More about : KLHL21 |
| Long gene name: |
kelch like family member 21 |
| Synonyms gene name: |
kelch-like 21 (Drosophila) |
| Synonyms: |
KIAA0469 |
| Locus: |
1p36, 31 |
| Discovery year: |
2004-12-23 |
| GenBank acession: |
AK090472 |
| Entrez gene record: |
9903 |
| RefSeq identity: |
NM_014851 |
| Classification: |
BTB domain containing Kelch like |
| Havana BLAST/BLAT: |
OTTHUMG00000001437 |