| Long name: |
HCF-1 Primary Polyclonal Antibody |
| Also known as: |
HCF-1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HCF-1 |
| Specificity: |
This is a highly specific antibody against HCF-1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HCF-1 |
| Gene ID number: |
3054 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also antagonizestransactivation by ZBTB17 and GABP2, As part of theNSL complex it may be involved in acetylation of nucleosomalhistone H4 on several lysine residues, Componentof a THAP1/THAP3-HCFC1-OGT complex that is required for theregulation of the transcriptional activity of RRM1, HCFC1 forms a multiprotein-DNAcomplex with the viral transactivator protein VP16 and POU2F1thereby enabling the transcription of the viral immediate earlygenes, In case of human herpessimplex virus (HSV) infection, Tethers the chromatin modifyingSet1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3histone deacetylase (HDAC) complexes (involved in the activationand repression of transcription, represses ZBTB17 activation ofthe p15(INK4b) promoter and inhibits its ability to recruit p300, respectively) together, Coactivator for EGR2 and GABP2, Involved in control of the cell cycle |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C1 factor, CFF, CFF, HCF, HCF 1, HCF C-terminal chain 6, HCF N-terminal chain 1, HCF N-terminal chain 2, HCF N-terminal chain 3, HCF N-terminal chain 4, HCF N-terminal chain 5, HCF N-terminal chain 6, HCF-1, HCF1, HCFC1_HUMAN, HFC1, Hcfc1, Host Cell Factor-1, Host cell factor, Host cell factor 1, Host cell factor C1, Host cell factor C1 (VP16 accessory protein), MGC70925, VCAF, VCAF, VP16 accessory protein, VP16 accessory protein, C1 factor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HCF-1 |
| Short name: |
HCF-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HCF-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4839 |
| Gene: |
HCFC1 |
More about : HCFC1 |
| Long gene name: |
host cell factor C1 |
| Synonyms gene: |
HFC1 MRX3 |
| Synonyms gene name: |
X-linked 3 host cell factor C1 (VP16-accessory protein) , mental retardation |
| Synonyms: |
HCF-1 HCF1 CFF VCAF MGC70925 PPP1R89 |
| Synonyms name: |
VP16-accessory protein protein phosphatase 1, regulatory subunit 89 |
| Locus: |
Xq28 |
| Discovery year: |
1994-10-14 |
| Entrez gene record: |
3054 |
| Pubmed identfication: |
8392914 23000143 |
| RefSeq identity: |
NM_005334 |
| Classification: |
X-linked mental retardation Protein phosphatase 1 regulatory subunits ATAC complex |
| Havana BLAST/BLAT: |
OTTHUMG00000024222 |
| Locus Specific Databases: |
Mental Retardation database |