| Long name: |
GGCX Primary Polyclonal Antibody |
| Also known as: |
GGCX PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GGCX |
| Specificity: |
This is a highly specific antibody against GGCX |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GGCX |
| Gene ID number: |
2677 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in the gene encoding GGCX are the cause of combined deficiency of vitamin K-dependent clotting factors 1 (VKCFD1) and PXE-like disorder with multiple coagulation factor deficiency, GGCX exists as a monomer and, GGCX functions to mediate the vitamin K-dependent carboxylation of glutamate residues on target proteins, Localized to the membrane of the endoplasmic reticulum, blood or bone function, both of which are characterized by abnormal skin, it accomplishes the post-translational changes that are necessary for the activity of all vitamin K-dependent proteins (such as blood coagulation and bone matrix proteins), thereby producing calcium binding gamma-carboxyglutamate (Gla) residues on these proteins and simultaneously converting vitamin K to vitamin K epoxide, via its ability to modify glutamate residues, GGCX is a 758 amino acid multi-pass membrane protein |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GC antibody GGCX, Gamma-glutamyl carboxylase, Peptidyl glutamate 4 carboxylase, Peptidyl-glutamate 4-carboxylase, VKCFD 1, VKCFD1, VKGC_HUMAN, Vitamin K dependent gamma carboxylase, Vitamin K gamma glutamyl carboxylase, Vitamin K-dependent gamma-carboxylase, Gamma glutamyl carboxylase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GGCX |
| Short name: |
GGCX Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GGCX (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4247 |
| Gene: |
GGCX |
More about : GGCX |
| Long gene name: |
gamma-glutamyl carboxylase |
| Synonyms: |
VKCFD1 |
| Synonyms name: |
vitamin K-dependent gamma-carboxylase |
| Locus: |
2p11, 2 |
| Discovery year: |
1994-07-04 |
| Entrez gene record: |
2677 |
| Pubmed identfication: |
1749935 |
| RefSeq identity: |
NM_000821 |
| Havana BLAST/BLAT: |
OTTHUMG00000130173 |
| Locus Specific Databases: |
LRG_592 |