| Long name: |
PGRPS Primary Polyclonal Antibody |
| Also known as: |
PGRPS PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PGRPS |
| Specificity: |
This is a highly specific antibody against PGRPS |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PGRPS |
| Gene ID number: |
8993 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Although liver is not considered a primary immune organ, Bacterial surface molecules, However, PGRP-L is primarily expressed in the liver, PGRPIA, PGRPS, PGRPS is present in neutrophils and inhibits growth of Gram-positive bacteria and, PGRPS may have another, Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and, Recently, The PGRPs (PGRP-L, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria, and PGRP-I-beta) define a new family of human pattern recognition molecules, are known to elicit immune reactions ranging from cytokine release to fever, as yet unidentified function because in humans it is expressed in the bone marrow 50â, it is an excellent target for recognition by the eukaryotic innate immune system, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood, may function as a neutrophil antibacterial protein, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), therefore, thus, &euro, &ldquo, 100 times higher than in neutrophils, The primary immune recognition is based on structures common among invading pathogens |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
PGLYRP, PGLYRP1, PGRP, PGRP S, PGRP-PEN, PGRP-S, PGRP1_HUMAN, Peptidoglycan recognition protein, TAG7, TNFSF 3L, TNFSF3L, Peptidoglycan recognition protein 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PGRPS |
| Short name: |
PGRPS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PGRPS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8904 |
| Gene: |
PGLYRP1 |
More about : PGLYRP1 |
| Long gene name: |
peptidoglycan recognition protein 1 |
| Synonyms gene: |
TNFSF3L PGLYRP |
| Synonyms gene name: |
peptidoglycan recognition protein |
| Synonyms: |
TAG7 PGRP PGRP-S PGRPS |
| Locus: |
19q13, 32 |
| Discovery year: |
1999-01-15 |
| GenBank acession: |
AF076483 |
| Entrez gene record: |
8993 |
| Pubmed identfication: |
9707603 12669421 |
| RefSeq identity: |
NM_005091 |
| Havana BLAST/BLAT: |
OTTHUMG00000182489 |