| Long name: |
Cy3 Conjugated, MDM4 POLYCLONAL ANTIBODY |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MDM4 |
| Specificity: |
This is a highly specific antibody against MDM4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
300-330/490 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human MDM4 |
| Gene ID number: |
4194 |
| Swiss Prot: |
O15151 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions, Inhibits degradation of MDM2, Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
MDMX HDMX |
| Properties: |
1 of the MDM4 ANTIBODY, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser |
| Gene target: |
MDM4 Conjugated |
| Short name: |
Conjugated, MDM4 ANTIBODY |
| Technique: |
antibody Conjugates |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Mdm4 p53 binding protein homolog (mouse) (Antibody to) |
| Alternative to gene target: |
BT, HDMX and MDMX and MRP1, MDM4 and IDBG-106054 and ENSG00000198625 and 4194, Mdm4 and IDBG-192393 and ENSMUSG00000054387 and 102641776, enzyme binding, nuclei, signal transduction by p53 class mediator and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045023 and G0 to G1 transition and biological process this GO :0050821 and protein stabilization and biological process this GO :0071157 and negative regulation of cell cycle arrest and biological process this GO :0071456 and cellular response to hypoxia and biological process, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0030330 and DNA damage response, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0019899 : enzyme binding, this GO :0008270 : zinc ion binding, this GO :0019899 : enzyme binding, 17248, 36413 and IDBG-628663 and ENSBTAG00000006255 and 100138492, 514225, Mdm4 p53 binding protein homolog (mouse) |
| Identity: |
6974 |
| Gene: |
MDM4 |
More about : MDM4 |
| Long gene name: |
MDM4, p53 regulator |
| Synonyms gene name: |
human homolog of, mouse double minute 4, p53 binding protein (mouse) Mdm4 p53 binding protein homolog (mouse) , p53-binding protein Mdm4, transformed 3T3 cell double minute 4 |
| Locus: |
1q32, 1 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
AF007111 |
| Entrez gene record: |
4194 |
| Pubmed identfication: |
9226370 14660608 |
| RefSeq identity: |
NM_002393 |
| Havana BLAST/BLAT: |
OTTHUMG00000035877 |