| Long name: |
FITC Conjugated, HAX1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HAX1 |
| Specificity: |
This is a highly specific antibody against HAX1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HAX1 |
| Gene ID number: |
10456 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease, HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1, It may also function in promoting cell survival, binding to its N-terminal region, so may play a role in mRNA stability and transport, RelevanceHAX1 associates with HS1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HS1BP1 HCLSBP1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HAX1 Conjugated |
| Short name: |
FITC Conjugated, HAX1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, HCLS1 associated protein X-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HAX1 and IDBG-102924 and ENSG00000143575 and 10456, HAX1 and IDBG-632533 and ENSBTAG00000013025 and 506895, HCLSBP1 and HS1BP1 and SCN3, Hax1 and IDBG-165357 and ENSMUSG00000027944 and 23897, nuclei, protein N-terminus binding, this GO :0005515 and protein binding and molecular function this GO :0005635 and nuclear envelope and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016529 and sarcoplasmic reticulum and cellular component this GO :0019904 and protein domain specific binding and molecular function this GO :0019966 and interleukin-1 binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030136 and clathrin-coated vesicle and cellular component this GO :0030833 and regulation of actin filament polymerization and biological process this GO :0030854 and positive regulation of granulocyte differentiation and biological process this GO :0031965 and nuclear membrane and cellular component this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :2000251 and positive regulation of actin cytoskeleton reorganization and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0019904 : protein domain specific binding and also this GO :0019966 : interleukin-1 binding and also this GO :0047485 : protein N-terminus binding, this GO :0019904 : protein domain specific binding, this GO :0019966 : interleukin-1 binding, this GO :0047485 : protein N-terminus binding, HCLS1 associated protein X-1 |
| Identity: |
16915 |
| Gene: |
HAX1 |
More about : HAX1 |
| Long gene name: |
HCLS1 associated protein X-1 |
| Synonyms name: |
HCLS1 (and PKD2) associated protein |
| Locus: |
1q21, 3 |
| Discovery year: |
2005-05-19 |
| GenBank acession: |
U68566 |
| Entrez gene record: |
10456 |
| Pubmed identfication: |
9058808 10760273 |
| RefSeq identity: |
NM_006118 |
| Havana BLAST/BLAT: |
OTTHUMG00000035978 |
| Locus Specific Databases: |
HAX1base: Mutation registry for severe congenital neutropenia (Kostmann disease) LRG_64 |