| Long name: |
RNF144B Primary Polyclonal Antibody |
| Also known as: |
RNF144B PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RNF144B |
| Specificity: |
This is a highly specific antibody against RNF144B |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IBRDC2/RING finger protein 144B |
| Gene ID number: |
255488 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
But, However, Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism, a pro-apoptotic protein, and highest levels detectable in heart, it is not an anti-apoptotic protein per se, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, ovary and testis, thereby promoting their degradation, ultimately leading to protection of cell death, with lowest levels in brain and thymus, E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, Tissue specificity: Broadly expressed |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E3 ubiquitin-protein ligase RNF144B, IBR domain containing 2, IBR domain containing protein 2, IBR domain-containing protein 2, IBRDC 2, IBRDC2, PIR2, R144B_HUMAN, RING finger protein 144B, RING finger protein 144B, RNF 144B, RNF144B, Ring finger 144B, p53 inducible RING finger protein, p53-inducible RING finger protein, p53RFP, E3 ubiquitin protein ligase RNF144B |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RNF144B |
| Short name: |
RNF144B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ring finger protein 144B (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Plasma membranes, RNF144B and IDBG-64050 and ENSG00000137393 and 255488, Rnf144b and IDBG-149475 and ENSMUSG00000038068 and 218215, ligase activity, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016874 and ligase activity and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, 66635 and IDBG-635837 and ENSBTAG00000009055 and 524166, ring finger protein 144B |
| Identity: |
21578 |
| Gene: |
RNF144B |
More about : RNF144B |
| Long gene name: |
ring finger protein 144B |
| Synonyms gene: |
IBRDC2 |
| Synonyms gene name: |
IBR domain containing 2 |
| Synonyms: |
bA528A10, 3 P53RFP |
| Locus: |
6p22, 3 |
| Discovery year: |
2003-06-25 |
| GenBank acession: |
AK096832 |
| Entrez gene record: |
255488 |
| RefSeq identity: |
XM_172581 |
| Classification: |
Ring finger proteins RBR E3 ubiquitin ligases |
| Havana BLAST/BLAT: |
OTTHUMG00000014322 |