| Long name: |
PPM1F Primary Polyclonal Antibody |
| Also known as: |
PPM1F PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PPM1F |
| Specificity: |
This is a highly specific antibody against PPM1F |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PPM1F |
| Gene ID number: |
9647 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
An alternatively spliced transcript variant has been identified, Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase, Jul 2008], PP2C family members are known to be negative regulators of cell stress response pathways, The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis, This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), [provided by RefSeq, a protein kinase mediating biological effects downstream of Rho GTPases, and thus block the effects of p21-activated kinase 1 (PAK), but its full-length nature has not been determined, The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CaM-kinase phosphatase, KIAA0015, POPX2, PPM1F_HUMAN, Partner of PIX 2, Protein phosphatase 1F, hFEM-2, Ca2+/calmodulin-dependent protein kinase phosphatase, CaMKPase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PPM1F |
| Short name: |
PPM1F Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
1F (Antibody to), Mg2+/Mn2+ dependent, protein phosphatase |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
1F, CAMKP and CaMKPase and FEM-2 and hFEM-2 and POPX2, Cytoplasm, DNA-templated and biological process this GO :0045927 and positive regulation of growth and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, Mg2+/Mn2+ dependent, PPM1F and IDBG-2163 and ENSG00000100034 and 9647, PPM1F and IDBG-637531 and ENSBTAG00000006938 and 618210, Ppm1f and IDBG-137609 and ENSMUSG00000026181 and 68606, metal ion binding, this GO :0003824 and catalytic activity and molecular function this GO :0004722 and protein serine/threonine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006470 and protein dephosphorylation and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010634 and positive regulation of epithelial cell migration and biological process this GO :0010811 and positive regulation of cell-substrate adhesion and biological process this GO :0016576 and histone dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0033137 and negative regulation of peptidyl-serine phosphorylation and biological process this GO :0033192 and calmodulin-dependent protein phosphatase activity and molecular function this GO :0035690 and cellular response to drug and biological process this GO :0035970 and peptidyl-threonine dephosphorylation and biological process this GO :0043234 and protein complex and cellular component this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044387 and negative regulation of protein kinase activity by regulation of protein phosphorylation and biological process this GO :0045892 and negative regulation of transcription, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004722 : protein serine/threonine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0016791 : phosphatase activity and also this GO :0033192 : calmodulin-dependent protein phosphatase activity and also this GO :0046872 : metal ion binding, this GO :0004722 : protein serine/threonine phosphatase activity, this GO :0005515 : protein binding, this GO :0016791 : phosphatase activity, this GO :0033192 : calmodulin-dependent protein phosphatase activity, this GO :0046872 : metal ion binding, protein phosphatase |
| Identity: |
19388 |
| Gene: |
PPM1F |
More about : PPM1F |
| Long gene name: |
Mg2+/Mn2+ dependent 1F , protein phosphatase |
| Synonyms gene name: |
1F , Mg2+/Mn2+ dependent, protein phosphatase 1F (PP2C domain containing) protein phosphatase |
| Synonyms: |
FEM-2 KIAA0015 POPX2 CaMKPase CAMKP |
| Synonyms name: |
partner of PIX 2 Ca(2+)/calmodulin-dependent protein kinase phosphatase |
| Locus: |
22q11, 22 |
| Discovery year: |
2002-11-28 |
| GenBank acession: |
D13640 |
| Entrez gene record: |
9647 |
| Pubmed identfication: |
11864573 11559703 |
| RefSeq identity: |
NM_014634 |
| Classification: |
Mg2+/Mn2+ dependent , Protein phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000150835 |