| Long name: |
ALEXA FLUOR 488 Conjugated, Galactosidase alpha Polyclonal Antibody |
| Also known as: |
Anti-Galactosidase alpha PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Galactosidase alpha |
| Specificity: |
This is a highly specific antibody against Galactosidase alpha |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
127-148/429 |
| Subcellular location: |
Lysosome |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Galactosidase alpha |
| Gene ID Number: |
2717 |
| Swiss Prot: |
P06280 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Clinical recognition in males results from characteristic skin lesions (angiokeratomas) over the lower trunk, Death results from renal failure, Defects in GLA are the cause of Fabry's disease (FD), FD is a rare X-linked sphingolipidosis disease where glycolipid accumulates in many tissues, Heterozygous females may exhibit the disorder in an attenuated form, Patients may show ocular deposits, and burning pain in the extremities, cardiac or cerebral complications of hypertension or other vascular disease, febrile episodes, galactomannans and galactohydrolase, including galactose oligosaccharides, non reducing alpha D galactose residues in alpha D galactosides, they are more likely to show corneal opacities, Galactosidase alpha is involved in the hydrolysis of terminal |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
GALA |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Galactosidase alpha Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Galactosidase alpha |
| Short name: |
Galactosidase alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Galactosidase a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4296 |
| Gene: |
GLA |
More about : GLA |
| Long gene name: |
galactosidase alpha |
| Locus: |
Xq22, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X16889 |
| Entrez gene record: |
2717 |
| Havana BLAST/BLAT: |
OTTHUMG00000022026 |
| Locus Specific Databases: |
Mental Retardation database LRG_672 |