| Long name: |
ALEXA FLUOR 350 Conjugated, Bcl2 modifying factor Antibody |
| Also known as: |
Anti-Bcl2 modying factor PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Bcl2 modying factor |
| Specificity: |
This is a highly specific antibody against Bcl2 modying factor |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bcl2 modifying factor |
| Gene ID Number: |
90427 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BID, Bad, Bcl-2 modifying factor (Bmf) is a BH3-only protein that binds prosurvival Bcl-2 family members to initiate apoptosis, Bik, Bim, Binding results in a caspase cascade leading to apoptosis, Bmf is sequestered to Myosin V motors on Actin in the cytoskeleton by associating with Dynein light chain 2 (DLC2) homodimers, Bmf is widely expressed in tissues such as pancreas, Bmf then translocates to the mitochondria, Hrk, If the cell undergoes loss of attachment (anoikis), NOXA, PUMA and Bmf, The BH3 domain of Bmf facilitates binding to a hydrophobic groove on the surface of Bcl-2, The gene encoding Bmf maps to chromosome 15q14, and in hematopoietic tissues, are proapoptotic members of the Bcl-2 family, liver and kidney, the cytoskeleton is disrupted and Bmf is released from DLC2, where Bcl-2 (an anti-apoptotic family member) is sequestered, which include Blk, The BH3-only proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
FLJ00065 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Description: |
Complex subunit associated factors are involved in hybridoma growth, Eosinohils, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, Aplha |
| Gene target: |
Bcl2 modifying factor |
| Short name: |
Bcl2 modifying factor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, B-cell CLL/lymphoma 2 modifying factor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24132 |
| Gene: |
BMF |
More about : BMF |
| Long gene name: |
Bcl2 modifying factor |
| Locus: |
15q15, 1 |
| Discovery year: |
2004-01-16 |
| GenBank acession: |
BC060783 |
| Entrez gene record: |
90427 |
| Pubmed identfication: |
11546872 |
| RefSeq identity: |
NM_033503 |
| Classification: |
BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT: |
OTTHUMG00000129875 |