| Long name: |
FITC Conjugated, TNIP2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TNIP2 |
| Specificity: |
This is a highly specific antibody against TNIP2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
200-230/430 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human TNIP2/ABIN2 |
| Gene ID number: |
79155 |
| Swiss Prot: |
Q8NFZ5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes, Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation, Involved in activation of the MEK/ERK signaling pathway during innate immune response, Involved in regulation of apoptosis in endothelial cells, May act as transcriptional coactivator when translocated to the nucleus, Required for stability of MAP3K8, promotes TEK agonist-stimulated endothelial survival, this function seems to be stimulus- and cell type specific, Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ABIN-2 MGC4289 KLIP FLIP1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TNIP2 Conjugated |
| Short name: |
FITC Conjugated, TNIP2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TNFAIP3 interacting protein 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0023035 and CD40 signaling pathway and biological process this GO :0031593 and polyubiquitin binding and molecular function this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0043032 and positive regulation of macrophage activation and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050821 and protein stabilization and biological process this GO :0050871 and positive regulation of B cell activation and biological process this GO :0070498 and interleukin-1-mediated signaling pathway and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, TNIP2 and IDBG-643700 and ENSBTAG00000015126 and 100336382, TNIP2 and IDBG-7609 and ENSG00000168884 and 79155, Tnip2 and IDBG-155271 and ENSMUSG00000059866 and 231130, nuclei, polyubiquitin binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0031593 : polyubiquitin binding, this GO :0019901 : protein kinase binding, this GO :0031593 : polyubiquitin binding, TNFAIP3 interacting protein 2 |
| Identity: |
19118 |
| Gene: |
TNIP2 |
More about : TNIP2 |
| Long gene name: |
TNFAIP3 interacting protein 2 |
| Locus: |
4p16, 3 |
| Discovery year: |
2002-10-03 |
| GenBank acession: |
BC002740 |
| Entrez gene record: |
79155 |
| Pubmed identfication: |
11390377 12933576 |
| RefSeq identity: |
NM_024309 |
| Havana BLAST/BLAT: |
OTTHUMG00000090267 |