| Long name: |
ALEXA FLUOR 488 Conjugated, TIRAP Polyclonal Antibody |
| Also known as: |
Anti-TIRAP PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TIRAP |
| Specificity: |
This is a highly specific antibody against TIRAP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TIRAP |
| Gene ID Number: |
114609 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts via IRAK2 and TRAF-6, MAPK1, MAPK3 and JNK, Positively regulates the production of TNF-alpha and interleukin-6, and resulting in cytokine secretion and the inflammatory response, leading to the activation of NF-kappa-B, Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
Mal wyatt |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TIRAP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TIRAP |
| Short name: |
TIRAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, toll-interleukin 1 receptor (TIR) domain containing adaptor protein (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TIRAP and IDBG-642760 and ENSBTAG00000021504 and 531079, TIRAP and IDBG-75811 and ENSG00000150455 and 114609, Tirap and IDBG-148134 and ENSMUSG00000032041 and 117149, bridging, bridging and also this GO :0035662 : Toll-like receptor 4 binding and also this GO :0035663 : Toll-like receptor 2 binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity, bridging and molecular function this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032648 and regulation of interferon-beta production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032738 and positive regulation of interleukin-15 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034137 and positive regulation of toll-like receptor 2 signaling pathway and biological process this GO :0034141 and positive regulation of toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034145 and positive regulation of toll-like receptor 4 signaling pathway and biological process this GO :0035662 and Toll-like receptor 4 binding and molecular function this GO :0035663 and Toll-like receptor 2 binding and molecular function this GO :0035665 and TIRAP-dependent toll-like receptor 4 signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0045410 and positive regulation of interleukin-6 biosynthetic process and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070935 and 3'-UTR-mediated mRNA stabilization and biological process this GO :0071221 and cellular response to bacterial lipopeptide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :0090073 and positive regulation of protein homodimerization activity and biological process this GO :2000340 and positive regulation of chemokine (C-X-C motif) ligand 1 production and biological process this GO :2000343 and positive regulation of chemokine (C-X-C motif) ligand 2 production and biological process, phosphatidylinositol-4, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005546 and phosphatidylinositol-4, this GO :0005080 : protein kinase C binding, this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0005546 : phosphatidylinositol-4, this GO :0005515 : protein binding, this GO :0005546 : phosphatidylinositol-4, this GO :0030674 : protein binding, this GO :0035662 : Toll-like receptor 4 binding, this GO :0035663 : Toll-like receptor 2 binding, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, 5-bisphosphate binding, 5-bisphosphate binding and also this GO :0030674 : protein binding, 5-bisphosphate binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030139 and endocytic vesicle and cellular component this GO :0030674 and protein binding, toll-interleukin 1 receptor (TIR) domain containing adaptor protein |
| Identity: |
17192 |
| Gene: |
TIRAP |
More about : TIRAP |
| Long gene name: |
TIR domain containing adaptor protein |
| Synonyms gene name: |
Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein |
| Synonyms name: |
MyD88 adapter-like |
| Locus: |
11q24, 2 |
| Discovery year: |
2003-06-05 |
| GenBank acession: |
AF378129 |
| Entrez gene record: |
114609 |
| Pubmed identfication: |
11526399 11544529 |
| RefSeq identity: |
NM_148910 |
| Classification: |
TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000140373 |