| Long name: |
Biotin Conjugated, SEMA4A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SEMA4A |
| Specificity: |
This is a highly specific antibody against SEMA4A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
360-410/761 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human SEMA4A |
| Gene ID number: |
64218 |
| Swiss Prot: |
Q9H3S1 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Inhibits angiogenesis, Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity), PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling, Plays a role in priming antigen-specific T-cells, Promotes axon growth cone collapse, Promotes phosphorylation of TIMD2, and thereby contributes to adaptive immunity, promotes differentiation of Th1 T-helper cells, Cell surface receptor for PLXNB1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
SemB FLJ12287 CORD10 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SEMA4A Conjugated |
| Short name: |
Conjugated, SEMA4A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
(semaphorin) 4A (Antibody to), biotinilated coupled, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, sema domain |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
(semaphorin) 4A, Plasma membranes, SEMA4A and IDBG-103399 and ENSG00000196189 and 64218, SEMA4A and IDBG-631665 and ENSBTAG00000012228 and 510239, Sema4a and IDBG-160873 and ENSMUSG00000028064 and 20351, immunoglobulin domain (Ig), protein binding, this GO :0001525 and angiogenesis and biological process this GO :0002292 and T cell differentiation involved in immune response and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0007409 and axonogenesis and biological process this GO :0007411 and axon guidance and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0010594 and regulation of endothelial cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0045063 and T-helper 1 cell differentiation and biological process this GO :0071526 and semaphorin-plexin signaling pathway and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, transmembrane domain (TM) and short cytoplasmic domain, sema domain |
| Identity: |
10729 |
| Gene: |
SEMA4A |
More about : SEMA4A |
| Long gene name: |
semaphorin 4A |
| Synonyms gene: |
SEMAB |
| Synonyms gene name: |
(semaphorin) 4A , immunoglobulin domain (Ig), sema domain, transmembrane domain (TM) and short cytoplasmic domain |
| Locus: |
1q22 |
| Discovery year: |
2004-04-22 |
| GenBank acession: |
AK022416 |
| Entrez gene record: |
64218 |
| Pubmed identfication: |
7748561 |
| RefSeq identity: |
NM_022367 |
| Classification: |
Semaphorins |
| Havana BLAST/BLAT: |
OTTHUMG00000014042 |