| Long name: |
LECT1 Primary Polyclonal Antibody |
| Also known as: |
LECT1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
LECT1 |
| Specificity: |
This is a highly specific antibody against LECT1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LECT1 |
| Gene ID number: |
11061 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alternative splicing results in multiple transcript variants encoding different isoforms, It may be involved also in the broad control of tissue vascularization during development, The C terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell derived chondromodulin 1 or chemotaxin 1, The N terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein, The mature protein inhibits angiogenesis and promotes chondrocyte growth, The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone, This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion, although no biological activity has yet been defined for it, secreted protein, The LECT1 gene encodes a glycosylated transmembrane protein which is cleaved to form a mature |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BRICD3, BRICHOS domain containing 3, CHM I, CHM1, Chondrosurfactant protein, LECT 1, LECT1_HUMAN, Leukocyte cell derived chemotaxin 1, chondromodulin, Chondromodulin I |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LECT1 |
| Short name: |
LECT1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
leukocyte cellular derived chemotaxin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BRICD3 and CHM-I and CHM1 and MYETS1, Extracellular, LECT1 and IDBG-35924 and ENSG00000136110 and 11061, LECT1 and IDBG-628626 and ENSBTAG00000025502 and 281683, Lect1 and IDBG-183045 and ENSMUSG00000022025 and 16840, this GO :0001501 and skeletal system development and biological process this GO :0001886 and endothelial cell morphogenesis and biological process this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0006029 and proteoglycan metabolic process and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0030948 and negative regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0051216 and cartilage development and biological process, leukocyte cell derived chemotaxin 1 |
| Identity: |
17005 |
| Gene: |
CNMD |
More about : CNMD |
| Long gene name: |
chondromodulin |
| Synonyms gene: |
MYETS1 LECT1 |
| Synonyms gene name: |
multiple myeloma tumor suppressor 1 leukocyte cell derived chemotaxin 1 |
| Synonyms: |
CHM-I CHM1 BRICD3 |
| Synonyms name: |
BRICHOS domain containing 3 |
| Locus: |
13q14, 3 |
| Discovery year: |
2003-02-18 |
| GenBank acession: |
AB006000 |
| Entrez gene record: |
11061 |
| Pubmed identfication: |
9731231 10103018 |
| Classification: |
BRICHOS domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000016980 |