| Long name: |
FITC Conjugated, GTP binding protein REM1 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GTP binding protein REM1 |
| Specificity: |
This is a highly specific antibody against GTP binding protein REM1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GTP binding protein REM1 |
| Gene ID number: |
28954 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Among these are nonconservative amino acid substitutions within guanine nucleotide binding and hydrolysis domains, GEM/kir, It has been reported that the GTP-bound form of a related Ras-like GTPase, REM, REM is phosphorylated in vivo and has been shown to interact with several 14-3-3 isoforms, The reduced channel activities are the result of a decreased a-subunit expression at the plasma membrane, There are data that suggest that REM similarly regulates Ca2+ channel expression, This inhibition of L-type Ca2+ channels prevents Ca2+-triggered exocytosis in hormone-secreting cells, and a conserved C-terminal sequence thought to mediate membrane association but lacking a classical isoprenylation motif, extended N- and C-termini, inhibits high-voltage activated Ca2+ channel activities by interacting directly with the ?subunit, is most highly expressed in cardiac muscle and is expressed at more moderate levels in lung, kidney and skeletal muscle, unique effector domains, with a predicted molecular weight of 32, 9 kDa, REM (Rad and Gem related GTP binding protein) is a member of the Rad/Gem/Kir subfamily of Ras-like GTPases and shares with other members of this subfamily some unusual structural features |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GES |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GTP binding protein REM1 Conjugated |
| Short name: |
FITC Conjugated, GTP binding protein REM1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GTP binding protein REM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15922 |
| Gene: |
REM1 |
More about : REM1 |
| Long gene name: |
RRAD and GEM like GTPase 1 |
| Synonyms gene: |
REM |
| Synonyms gene name: |
RAS (RAD and GEM)-like GTP-binding |
| Synonyms name: |
GTPase GES |
| Locus: |
20q11, 21 |
| Discovery year: |
2001-06-21 |
| GenBank acession: |
AF152863 |
| Entrez gene record: |
28954 |
| Pubmed identfication: |
10831614 14623965 22076634 |
| RefSeq identity: |
NM_014012 |
| Classification: |
RGK type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000032168 |