| Long name: |
Biotin Conjugated, Islet-1+2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Islet-1+2 |
| Specificity: |
This is a highly specific antibody against Islet-1+2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Islet-1/2 |
| Gene ID number: |
3670 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In developing mouse teeth, Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry, Islet-1 influences embryogenesis of the pancreatic islets of Langerhans and neural tube motor neuron differentiation, Islet-1 mediates patterning of dentition as an activator of Bmp4 expression in incisor (distal) areas of the stomatodeal epithelium, Islet-2 activity in newly generated motor neurons permits the diversification of visceral and somatic motor neuron subtypes in the developing spinal cord, Murine Islet-2 specifies retinal ganglion cell (RGC) laterality by repressing an ipsilateral pathfinding program unique to the ventral-temporal crescent (VTC) of RGCs in a Zic2- and EphB1-dependent manner, Islet-1 and Islet-2 contain amino-terminal LIM domains and a carboxy-terminal homeodomain and both influence developmental events |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ISL LIM homeobox 1, ISL1, ISL1 transcription factor, ISL1 transcription factor, ISL1 transcription factor LIM homeodomain, ISL1_HUMAN, Insulin gene enhancer protein ISL-1, Insulin related protein, Isl 1, Islet-1, Islet1, LIM/homeodomain, LIM/homeodomain islet 1, Insulin gene enhancer protein ISL 1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Islet-1+2 Conjugated |
| Short name: |
Conjugated, Islet-1+2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Islet-1+2 (Antibody to) |
| Alternative technique: |
antibodies |